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Presentations by group members at external events
We regularly present our work at seminars, specific meetings, and national and international conferences.
The philosophy of our system, which we call Rapid, is to deliver customised graphical user interfaces that allow a domain specialist to achieve certain tasks. These tasks make use of domain-specific applications that require much computational resources; a requirement which is satisfied by translating the task into one or several computational jobs to be performed on Grid Computing infrastructures and HPC facilities. The customised interface will allow the task to be performed without referring to terminology about the underlying computational infrastructure.
Characterising gene expression patterns is a crucial part of understanding the molecular determinants of embryonic development and the role of genes in disease. However, gene expression studies in human embryos need to overcome a number of difficulties. These include the sourcing and maintenance of collections of human material suitable for gene expression studies, bridging the expertise in both biological and informatics areas, and amassing and making accessible data from multiple laboratories and studies.
Research into human and animal health covers a vast array of biological components and functions. Yet strategies to simulate entire biological systems across multiple levels, by integrating many components and modelling their interactions, are largely undeveloped. Integration all the way from molecules to behaviour is a huge challenge. We will explore how this challenge can be approached by considering the components and interactions between these requited to build a virtual fly brain.
SINAPSE is the “Scottish Imaging Network: A Platform for Scientific Excellence”; it comprises a collaboration of six universities with research imaging facilities. Its objectives are to develop imaging expertise, support multi-centre clinical research in conjunction with the Clinical Research Networks, improve the ability of neuroscientists to collaborate on clinical trials and have a direct impact on patient health. One of the means to achieve these objectives is to provide an e-infrastructure that enables multi-centre clinical research through data sharing.
The Edinburgh Mouse Atlas aims to capture in-situ gene expression patterns in a common spatial framework. In this study, we construct a grammar to define spatial regions by combinations of these patterns. Combinations are formed by applying operators to curated gene expression patterns from the atlas, thereby resembling gene interactions in a spatial context. The space of combinations is searched using an evolutionary algorithm with the objective of finding the best match to a given target pattern.
Date and time:
Wednesday, 9 July, 2008 - 15:30
Location:
BioInformatics Research and Development 2008, Vienna, Austria.
Efficiently executing large-scale, data-intensive workflows such as Montage must take into account the volume and pattern of communication. When orchestrating data-centric workflows, centralised servers common to standard workflow systems can become a bottleneck to performance. However, standards-based workflow systems that rely on centralisation, e.g., Web service based frameworks, have many other benefits such as a wide user base and sustained support.
Date and time:
Wednesday, 25 June, 2008 - 17:30
Location:
ACM/IEEE International Symposium on High-Performance and Distributed Computing
