TY - CHAP T1 - Evolutionary Computation and Constraint Satisfaction Y1 - 2015 A1 - van Hemert, J. ED - Kacpryk, J. ED - Pedrycz, W. KW - constraint satisfaction KW - evolutionary computation AB - In this chapter we will focus on the combination of evolutionary computation techniques and constraint satisfaction problems. Constraint Programming (CP) is another approach to deal with constraint satisfaction problems. In fact, it is an important prelude to the work covered here as it advocates itself as an alternative approach to programming (Apt). The first step is to formulate a problem as a CSP such that techniques from CP, EC, combinations of the two (c.f., Hybrid) or other approaches can be deployed to solve the problem. The formulation of a problem has an impact on its complexity in terms of effort required to either find a solution or proof no solution exists. It is therefore vital to spend time on getting this right. Main differences between CP and EC. CP defines search as iterative steps over a search tree where nodes are partial solutions to the problem where not all variables are assigned values. The search then maintain a partial solution that satisfies all variables assigned values. Instead, in EC most often solver sample a space of candidate solutions where variables are all assigned values. None of these candidate solutions will satisfy all constraints in the problem until a solution is found. Another major difference is that many constraint solvers from CP are sound whereas EC solvers are not. A solver is sound if it always finds a solution if it exists. PB - Springer ER - TY - JOUR T1 - Precise montaging and metric quantification of retinal surface area from ultra-widefield fundus photography and fluorescein angiography JF - Ophthalmic Surg Lasers Imaging Retina Y1 - 2014 A1 - Croft, D.E. A1 - van Hemert, J. A1 - Wykoff, C.C. A1 - Clifton, D. A1 - Verhoek, M. A1 - Fleming, A. A1 - Brown, D.M. KW - medical KW - retinal imaging AB - BACKGROUND AND OBJECTIVE: Accurate quantification of retinal surface area from ultra-widefield (UWF) images is challenging due to warping produced when the retina is projected onto a two-dimensional plane for analysis. By accounting for this, the authors sought to precisely montage and accurately quantify retinal surface area in square millimeters. PATIENTS AND METHODS: Montages were created using Optos 200Tx (Optos, Dunfermline, U.K.) images taken at different gaze angles. A transformation projected the images to their correct location on a three-dimensional model. Area was quantified with spherical trigonometry. Warping, precision, and accuracy were assessed. RESULTS: Uncorrected, posterior pixels represented up to 79% greater surface area than peripheral pixels. Assessing precision, a standard region was quantified across 10 montages of the same eye (RSD: 0.7%; mean: 408.97 mm(2); range: 405.34-413.87 mm(2)). Assessing accuracy, 50 patients' disc areas were quantified (mean: 2.21 mm(2); SE: 0.06 mm(2)), and the results fell within the normative range. CONCLUSION: By accounting for warping inherent in UWF images, precise montaging and accurate quantification of retinal surface area in square millimeters were achieved. [Ophthalmic Surg Lasers Imaging Retina. 2014;45:312-317.]. VL - 45 ER - TY - JOUR T1 - Quantification of Ultra-Widefield Retinal Images JF - Retina Today Y1 - 2014 A1 - D.E. Croft A1 - C.C. Wykoff A1 - D.M. Brown A1 - van Hemert, J. A1 - M. Verhoek KW - medical KW - retinal imaging AB - Advances in imaging periodically lead to dramatic changes in the diagnosis, management, and study of retinal disease. For example, the innovation and wide-spread application of fluorescein angiography and optical coherence tomography (OCT) have had tremendous impact on the management of retinal disorders.1,2 Recently, ultra-widefield (UWF) imaging has opened a new window into the retina, allowing the capture of greater than 80% of the fundus with a single shot.3 With montaging, much of the remaining retinal surface area can be captured.4,5 However, to maximize the potential of these new modalities, accurate quantification of the pathology they capture is critical. UR - http://www.bmctoday.net/retinatoday/pdfs/0514RT_imaging_Croft.pdf ER - TY - JOUR T1 - Automatic extraction of retinal features from colour retinal images for glaucoma diagnosis: A review JF - Computerized Medical Imaging and Graphics Y1 - 2013 A1 - Haleem, M.S. A1 - Han, L. A1 - van Hemert, J. A1 - Li, B. KW - retinal imaging AB - Glaucoma is a group of eye diseases that have common traits such as, high eye pressure, damage to the Optic Nerve Head and gradual vision loss. It affects peripheral vision and eventually leads to blindness if left untreated. The current common methods of pre-diagnosis of Glaucoma include measurement of Intra-Ocular Pressure (IOP) using Tonometer, Pachymetry, Gonioscopy; which are performed manually by the clinicians. These tests are usually followed by Optic Nerve Head (ONH) Appearance examination for the confirmed diagnosis of Glaucoma. The diagnoses require regular monitoring, which is costly and time consuming. The accuracy and reliability of diagnosis is limited by the domain knowledge of different ophthalmologists. Therefore automatic diagnosis of Glaucoma attracts a lot of attention. This paper surveys the state-of-the-art of automatic extraction of anatomical features from retinal images to assist early diagnosis of the Glaucoma. We have conducted critical evaluation of the existing automatic extraction methods based on features including Optic Cup to Disc Ratio (CDR), Retinal Nerve Fibre Layer (RNFL), Peripapillary Atrophy (PPA), Neuroretinal Rim Notching, Vasculature Shift, etc., which adds value on efficient feature extraction related to Glaucoma diagnosis. VL - 37 SN - 0895-6111 UR - http://linkinghub.elsevier.com/retrieve/pii/S0895611113001468?showall=true ER - TY - CONF T1 - Automatic Extraction of the Optic Disc Boundary for Detecting Retinal Diseases T2 - 14th {IASTED} International Conference on Computer Graphics and Imaging (CGIM) Y1 - 2013 A1 - M.S. Haleem A1 - L. Han A1 - B. Li A1 - A. Nisbet A1 - van Hemert, J. A1 - M. Verhoek ED - L. Linsen ED - M. Kampel KW - retinal imaging AB - In this paper, we propose an algorithm based on active shape model for the extraction of Optic Disc boundary. The determination of Optic Disc boundary is fundamental to the automation of retinal eye disease diagnosis because the Optic Disc Center is typically used as a reference point to locate other retinal structures, and any structural change in Optic Disc, whether textural or geometrical, can be used to determine the occurrence of retinal diseases such as Glaucoma. The algorithm is based on determining a model for the Optic Disc boundary by learning patterns of variability from a training set of annotated Optic Discs. The model can be deformed so as to reflect the boundary of Optic Disc in any feasible shape. The algorithm provides some initial steps towards automation of the diagnostic process for retinal eye disease in order that more patients can be screened with consistent diagnoses. The overall accuracy of the algorithm was 92% on a set of 110 images. JF - 14th {IASTED} International Conference on Computer Graphics and Imaging (CGIM) PB - {ACTA} Press ER - TY - BOOK T1 - The DATA Bonanza: Improving Knowledge Discovery in Science, Engineering, and Business T2 - Wiley Series on Parallel and Distributed Computing (Editor: Albert Y. Zomaya) Y1 - 2013 A1 - Atkinson, Malcolm P. A1 - Baxter, Robert M. A1 - Peter Brezany A1 - Oscar Corcho A1 - Michelle Galea A1 - Parsons, Mark A1 - Snelling, David A1 - van Hemert, Jano KW - Big Data KW - Data Intensive KW - data mining KW - Data Streaming KW - Databases KW - Dispel KW - Distributed Computing KW - Knowledge Discovery KW - Workflows AB - With the digital revolution opening up tremendous opportunities in many fields, there is a growing need for skilled professionals who can develop data-intensive systems and extract information and knowledge from them. This book frames for the first time a new systematic approach for tackling the challenges of data-intensive computing, providing decision makers and technical experts alike with practical tools for dealing with our exploding data collections. Emphasising data-intensive thinking and interdisciplinary collaboration, The DATA Bonanza: Improving Knowledge Discovery in Science, Engineering, and Business examines the essential components of knowledge discovery, surveys many of the current research efforts worldwide, and points to new areas for innovation. Complete with a wealth of examples and DISPEL-based methods demonstrating how to gain more from data in real-world systems, the book: * Outlines the concepts and rationale for implementing data-intensive computing in organisations * Covers from the ground up problem-solving strategies for data analysis in a data-rich world * Introduces techniques for data-intensive engineering using the Data-Intensive Systems Process Engineering Language DISPEL * Features in-depth case studies in customer relations, environmental hazards, seismology, and more * Showcases successful applications in areas ranging from astronomy and the humanities to transport engineering * Includes sample program snippets throughout the text as well as additional materials on a companion website The DATA Bonanza is a must-have guide for information strategists, data analysts, and engineers in business, research, and government, and for anyone wishing to be on the cutting edge of data mining, machine learning, databases, distributed systems, or large-scale computing. JF - Wiley Series on Parallel and Distributed Computing (Editor: Albert Y. Zomaya) PB - John Wiley & Sons Inc. SN - 978-1-118-39864-7 ER - TY - CHAP T1 - Data-Intensive Analysis T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Oscar Corcho A1 - van Hemert, Jano ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - data mining KW - Data-Analysis Experts KW - Data-Intensive Analysis KW - Knowledge Discovery AB - Part II: "Data-intensive Knowledge Discovery", focuses on the needs of data-analysis experts. It illustrates the problem-solving strategies appropriate for a data-rich world, without delving into the details of underlying technologies. It should engage and inform data-analysis specialists, such as statisticians, data miners, image analysts, bio-informaticians or chemo-informaticians, and generate ideas pertinent to their application areas. Chapter 5: "Data-intensive Analysis", introduces a set of common problems that data-analysis experts often encounter, by means of a set of scenarios of increasing levels of complexity. The scenarios typify knowledge discovery challenges and the presented solutions provide practical methods; a starting point for readers addressing their own data challenges. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - Data-Intensive Components and Usage Patterns T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Oscar Corcho ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data Analysis KW - data mining KW - Data-Intensive Components KW - Registry KW - Workflow Libraries KW - Workflow Sharing AB - Chapter 7: "Data-intensive components and usage patterns", provides a systematic review of the components that are commonly used in knowledge discovery tasks as well as common patterns of component composition. That is, it introduces the processing elements from which knowledge discovery solutions are built and common composition patterns for delivering trustworthy information. It reflects on how these components and patterns are evolving in a data-intensive context. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - The Data-Intensive Survival Guide T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Malcolm Atkinson ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data-Analysis Experts KW - Data-Intensive Architecture KW - Data-intensive Computing KW - Data-Intensive Engineers KW - Datascopes KW - Dispel KW - Domain Experts KW - Intellectual Ramps KW - Knowledge Discovery KW - Workflows AB - Chapter 3: "The data-intensive survival guide", presents an overview of all of the elements of the proposed data-intensive strategy. Sufficient detail is presented for readers to understand the principles and practice that we recommend. It should also provide a good preparation for readers who choose to sample later chapters. It introduces three professional viewpoints: domain experts, data-analysis experts, and data-intensive engineers. Success depends on a balanced approach that develops the capacity of all three groups. A data-intensive architecture provides a flexible framework for that balanced approach. This enables the three groups to build and exploit data-intensive processes that incrementally step from data to results. A language is introduced to describe these incremental data processes from all three points of view. The chapter introduces ‘datascopes’ as the productized data-handling environments and ‘intellectual ramps’ as the ‘on ramps’ for the highways from data to knowledge. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - Data-Intensive Thinking with DISPEL T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Malcolm Atkinson ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data-Intensive Machines KW - Data-Intensive Thinking, Data-intensive Computing KW - Dispel KW - Distributed Computing KW - Knowledge Discovery AB - Chapter 4: "Data-intensive thinking with DISPEL", engages the reader with technical issues and solutions, by working through a sequence of examples, building up from a sketch of a solution to a large-scale data challenge. It uses the DISPEL language extensively, introducing its concepts and constructs. It shows how DISPEL may help designers, data-analysts, and engineers develop solutions to the requirements emerging in any data-intensive application domain. The reader is taken through simple steps initially, this then builds to conceptually complex steps that are necessary to cope with the realities of real data providers, real data, real distributed systems, and long-running processes. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Inc. ER - TY - CHAP T1 - Definition of the DISPEL Language T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Paul Martin A1 - Yaikhom, Gagarine ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data Streaming KW - Data-intensive Computing KW - Dispel AB - Chapter 10: "Definition of the DISPEL language", describes the novel aspects of the DISPEL language: its constructs, capabilities, and anticipated programming style. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business T3 - {Parallel and Distributed Computing, series editor Albert Y. Zomaya} PB - John Wiley & Sons Inc. ER - TY - CHAP T1 - The Digital-Data Challenge T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Malcolm Atkinson A1 - Parsons, Mark ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Big Data KW - Data-intensive Computing, Knowledge Discovery KW - Digital Data KW - Digital-Data Revolution AB - Part I: Strategies for success in the digital-data revolution, provides an executive summary of the whole book to convince strategists, politicians, managers, and educators that our future data-intensive society requires new thinking, new behavior, new culture, and new distribution of investment and effort. This part will introduce the major concepts so that readers are equipped to discuss and steer their organization’s response to the opportunities and obligations brought by the growing wealth of data. It will help readers understand the changing context brought about by advances in digital devices, digital communication, and ubiquitous computing. Chapter 1: The digital-data challenge, will help readers to understand the challenges ahead in making good use of the data and introduce ideas that will lead to helpful strategies. A global digital-data revolution is catalyzing change in the ways in which we live, work, relax, govern, and organize. This is a significant change in society, as important as the invention of printing or the industrial revolution, but more challenging because it is happening globally at lnternet speed. Becoming agile in adapting to this new world is essential. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - The Digital-Data Revolution T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Malcolm Atkinson ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data KW - Information KW - Knowledge KW - Knowledge Discovery KW - Social Impact of Digital Data KW - Wisdom, Data-intensive Computing AB - Chapter 2: "The digital-data revolution", reviews the relationships between data, information, knowledge, and wisdom. It analyses and quantifies the changes in technology and society that are delivering the data bonanza, and then reviews the consequential changes via representative examples in biology, Earth sciences, social sciences, leisure activity, and business. It exposes quantitative details and shows the complexity and diversity of the growing wealth of data, introducing some of its potential benefits and examples of the impediments to successfully realizing those benefits. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - DISPEL Development T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Adrian Mouat A1 - Snelling, David ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Diagnostics KW - Dispel KW - IDE KW - Libraries KW - Processing Elements AB - Chapter 11: "DISPEL development", describes the tools and libraries that a DISPEL developer might expect to use. The tools include those needed during process definition, those required to organize enactment, and diagnostic aids for developers of applications and platforms. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Inc. ER - TY - CHAP T1 - DISPEL Enactment T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Chee Sun Liew A1 - Krause, Amrey A1 - Snelling, David ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data Streaming KW - Data-Intensive Engineering KW - Dispel KW - Workflow Enactment AB - Chapter 12: "DISPEL enactment", describes the four stages of DISPEL enactment. It is targeted at the data-intensive engineers who implement enactment services. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Inc. ER - TY - JOUR T1 - Exploiting Parallel R in the Cloud with SPRINT JF - Methods of Information in Medicine Y1 - 2013 A1 - Piotrowski, Michal A1 - Gary McGilvary A1 - Sloan, Terence A1 - Mewissen, Muriel A1 - Ashley Lloyd A1 - Forster, Thorsten A1 - Mitchell, Lawrence A1 - Ghazal, Peter A1 - Hill, Jon AB - Background: Advances in DNA Microarray devices and next-generation massively parallel DNA sequencing platforms have led to an exponential growth in data availability but the arising opportunities require adequate computing resources. High Performance Computing (HPC) in the Cloud offers an affordable way of meeting this need. Objectives: Bioconductor, a popular tool for high-throughput genomic data analysis, is distributed as add-on modules for the R statistical programming language but R has no native capabilities for exploiting multi-processor architectures. SPRINT is an R package that enables easy access to HPC for genomics researchers. This paper investigates: setting up and running SPRINT-enabled genomic analyses on Amazon’s Elastic Compute Cloud (EC2), the advantages of submitting applications to EC2 from different parts of the world and, if resource underutilization can improve application performance. Methods: The SPRINT parallel implementations of correlation, permutation testing, partitioning around medoids and the multi-purpose papply have been benchmarked on data sets of various size on Amazon EC2. Jobs have been submitted from both the UK and Thailand to investigate monetary differences. Results: It is possible to obtain good, scalable performance but the level of improvement is dependent upon the nature of algorithm. Resource underutilization can further improve the time to result. End-user’s location impacts on costs due to factors such as local taxation. Conclusions: Although not designed to satisfy HPC requirements, Amazon EC2 and cloud computing in general provides an interesting alternative and provides new possibilities for smaller organisations with limited funds. VL - 52 IS - 1 ER - TY - CHAP T1 - Foreword T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Tony Hey ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Big Data KW - Data-intensive Computing, Knowledge Discovery JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - Platforms for Data-Intensive Analysis T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Snelling, David ED - Malcolm Atkinson ED - Baxter, Robert M. ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data-Intensive Engineering KW - Data-Intensive Systems KW - Dispel KW - Distributed Systems AB - Part III: "Data-intensive engineering", is targeted at technical experts who will develop complex applications, new components, or data-intensive platforms. The techniques introduced may be applied very widely; for example, to any data-intensive distributed application, such as index generation, image processing, sequence comparison, text analysis, and sensor-stream monitoring. The challenges, methods, and implementation requirements are illustrated by making extensive use of DISPEL. Chapter 9: "Platforms for data-intensive analysis", gives a reprise of data-intensive architectures, examines the business case for investing in them, and introduces the stages of data-intensive workflow enactment. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - Preface T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Malcolm Atkinson ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Big Data, Data-intensive Computing, Knowledge Discovery AB - Who should read the book and why. The structure and conventions used. Suggested reading paths for different categories of reader. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - Problem Solving in Data-Intensive Knowledge Discovery T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Oscar Corcho A1 - van Hemert, Jano ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data-Analysis Experts KW - Data-Intensive Analysis KW - Design Patterns for Knowledge Discovery KW - Knowledge Discovery AB - Chapter 6: "Problem solving in data-intensive knowledge discovery", on the basis of the previous scenarios, this chapter provides an overview of effective strategies in knowledge discovery, highlighting common problem-solving methods that apply in conventional contexts, and focusing on the similarities and differences of these methods. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CHAP T1 - Sharing and Reuse in Knowledge Discovery T2 - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business Y1 - 2013 A1 - Oscar Corcho ED - Malcolm Atkinson ED - Rob Baxter ED - Peter Brezany ED - Oscar Corcho ED - Michelle Galea ED - Parsons, Mark ED - Snelling, David ED - van Hemert, Jano KW - Data-Intensive Analysis KW - Knowledge Discovery KW - Ontologies KW - Semantic Web KW - Sharing AB - Chapter 8: "Sharing and re-use in knowledge discovery", introduces more advanced knowledge discovery problems, and shows how improved component and pattern descriptions facilitate re-use. This supports the assembly of libraries of high level components well-adapted to classes of knowledge discovery methods or application domains. The descriptions are made more powerful by introducing notations from the semantic Web. JF - THE DATA BONANZA: Improving Knowledge Discovery for Science, Engineering and Business PB - John Wiley & Sons Ltd. ER - TY - CONF T1 - Towards automatic detection of abnormal retinal capillaries in ultra-widefield-of-view retinal angiographic exams T2 - Conf Proc IEEE Eng Med Biol Soc Y1 - 2013 A1 - Zutis, K. A1 - Trucco, E. A1 - Hubschman, J. P. A1 - Reed, D. A1 - Shah, S. A1 - van Hemert, J. KW - retinal imaging AB - Retinal capillary abnormalities include small, leaky, severely tortuous blood vessels that are associated with a variety of retinal pathologies. We present a prototype image-processing system for detecting abnormal retinal capillary regions in ultra-widefield-of-view (UWFOV) fluorescein angiography exams of the human retina. The algorithm takes as input an UWFOV FA frame and returns the candidate regions identified. An SVM classifier is trained on regions traced by expert ophthalmologists. Tests with a variety of feature sets indicate that edge features and allied properties differentiate best between normal and abnormal retinal capillary regions. Experiments with an initial set of images from patients showing branch retinal vein occlusion (BRVO) indicate promising area under the ROC curve of 0.950 and a weighted Cohen's Kappa value of 0.822. JF - Conf Proc IEEE Eng Med Biol Soc ER - TY - CONF T1 - User-friendly workflows in quantum chemistry T2 - IWSG 2013 Y1 - 2013 A1 - Herres-Pawlis, Sonja A1 - Balaskó, Ákos A1 - Birkenheuer, Georg A1 - Brinkmann, André A1 - Gesing, Sandra A1 - Grunzke, Richard A1 - Hoffmann, Alexander A1 - Kacsuk, Peter A1 - Krüger, Jens A1 - Packschies, Lars A1 - Terstyansky, Gabor A1 - Weingarten, Noam JF - IWSG 2013 PB - CEUR Workshop Proceedings CY - Zurich, Switzerland UR - http://ceur-ws.org/Vol-993/paper14.pdf ER - TY - CONF T1 - A Data Driven Science Gateway for Computational Workflows T2 - UNICORE Summit 2012 Y1 - 2012 A1 - Grunzke, Richard A1 - Birkenheuer, G. A1 - Blunk, D. A1 - Breuers, S. A1 - Brinkmann, A. A1 - Gesing, Sandra A1 - Herres-Pawlis, S A1 - Kohlbacher, O. A1 - Krüger, J. A1 - Kruse, M. A1 - Müller-Pfefferkorn, R. A1 - Schäfer, P. A1 - Schuller, B. A1 - Steinke, T. A1 - Zink, A. JF - UNICORE Summit 2012 ER - TY - JOUR T1 - EnzML: multi-label prediction of enzyme classes using InterPro signatures. JF - BMC Bioinformatics Y1 - 2012 A1 - De Ferrari, Luna A1 - Stuart Aitken A1 - van Hemert, Jano A1 - Goryanin, Igor AB - BACKGROUND: Manual annotation of enzymatic functions cannot keep up with automatic genome sequencing. In this work we explore the capacity of InterPro sequence signatures to automatically predict enzymatic function. RESULTS: We present EnzML, a multi-label classification method that can efficiently account also for proteins with multiple enzymatic functions: 50,000 in UniProt. EnzML was evaluated using a standard set of 300,747 proteins for which the manually curated Swiss-Prot and KEGG databases have agreeing Enzyme Commission (EC) annotations. EnzML achieved more than 98% subset accuracy (exact match of all correct Enzyme Commission classes of a protein) for the entire dataset and between 87 and 97% subset accuracy in reannotating eight entire proteomes: human, mouse, rat, mouse-ear cress, fruit fly, the S. pombe yeast, the E. coli bacterium and the M. jannaschii archaebacterium. To understand the role played by the dataset size, we compared the cross-evaluation results of smaller datasets, either constructed at random or from specific taxonomic domains such as archaea, bacteria, fungi, invertebrates, plants and vertebrates. The results were confirmed even when the redundancy in the dataset was reduced using UniRef100, UniRef90 or UniRef50 clusters. CONCLUSIONS: InterPro signatures are a compact and powerful attribute space for the prediction of enzymatic function. This representation makes multi-label machine learning feasible in reasonable time (30 minutes to train on 300,747 instances with 10,852 attributes and 2,201 class values) using the Mulan Binary Relevance Nearest Neighbours algorithm implementation (BR-kNN). VL - 13 ER - TY - CONF T1 - The MoSGrid Community - From National to International Scale T2 - EGI Community Forum 2012 Y1 - 2012 A1 - Gesing, Sandra A1 - Herres-Pawlis, Sonja A1 - Birkenheuer, Georg A1 - Brinkmann, André A1 - Grunzke, Richard A1 - Kacsuk, Peter A1 - Kohlbacher, Oliver A1 - Kozlovszky, Miklos A1 - Krüger, Jens A1 - Müller-Pfefferkorn, Ralph A1 - Schäfer, Patrick A1 - Steinke, Thomas JF - EGI Community Forum 2012 ER - TY - CONF T1 - MoSGrid: Progress of Workflow driven Chemical Simulations T2 - Grid Workflow Workshop 2011 Y1 - 2012 A1 - Birkenheuer, Georg A1 - Blunk, Dirk A1 - Breuers, Sebastian A1 - Brinkmann, André A1 - Fels, Gregor A1 - Gesing, Sandra A1 - Grunzke, Richard A1 - Herres-Pawlis, Sonja A1 - Kohlbacher, Oliver A1 - Krüger, Jens A1 - Packschies, Lars A1 - Schäfer, Patrick A1 - Schuller, B. A1 - Schuster, Johannes A1 - Steinke, Thomas A1 - Szikszay Fabri, Anna A1 - Wewior, Martin A1 - Müller-Pfefferkorn, Ralph A1 - Kohlbacher, Oliver JF - Grid Workflow Workshop 2011 PB - CEUR Workshop Proceedings ER - TY - CHAP T1 - Multi-agent Negotiation of Virtual Machine Migration Using the Lightweight Coordination Calculus T2 - Agent and Multi-Agent Systems. Technologies and Applications Y1 - 2012 A1 - Anderson, Paul A1 - Shahriar Bijani A1 - Vichos, Alexandros ED - Jezic, Gordan ED - Kusek, Mario ED - Nguyen, Ngoc-Thanh ED - Howlett, Robert ED - Jain, Lakhmi JF - Agent and Multi-Agent Systems. Technologies and Applications T3 - Lecture Notes in Computer Science PB - Springer Berlin / Heidelberg VL - 7327 SN - 978-3-642-30946-5 UR - http://dx.doi.org/10.1007/978-3-642-30947-2_16 ER - TY - CONF T1 - A Science Gateway Getting Ready for Serving the International Molecular Simulation Community T2 - Proceedings of Science Y1 - 2012 A1 - Gesing, Sandra A1 - Herres-Pawlis, Sonja A1 - Birkenheuer, Georg A1 - Brinkmann, André A1 - Grunzke, Richard A1 - Kacsuk, Peter A1 - Kohlbacher, Oliver A1 - Kozlovszky, Miklos A1 - Krüger, Jens A1 - Müller-Pfefferkorn, Ralph A1 - Schäfer, Patrick A1 - Steinke, Thomas JF - Proceedings of Science ER - TY - JOUR T1 - A Single Sign-On Infrastructure for Science Gateways on a Use Case for Structural Bioinformatics JF - Journal of Grid Computing Y1 - 2012 A1 - Gesing, Sandra A1 - Grunzke, Richard A1 - Krüger, Jens A1 - Birkenheuer, Georg A1 - Wewior, Martin A1 - Schäfer, Patrick A1 - Schuller, Bernd A1 - Schuster, Johannes A1 - Herres-Pawlis, Sonja A1 - Breuers, Sebastian A1 - Balaskó, Ákos A1 - Kozlovszky, Miklos A1 - Fabri, AnnaSzikszay A1 - Packschies, Lars A1 - Kacsuk, Peter A1 - Blunk, Dirk A1 - Steinke, Thomas A1 - Brinkmann, André A1 - Fels, Gregor A1 - Müller-Pfefferkorn, Ralph A1 - Jäkel, René A1 - Kohlbacher, Oliver KW - DCIs KW - Science gateway KW - security KW - Single sign-on KW - Structural bioinformatics VL - 10 UR - http://dx.doi.org/10.1007/s10723-012-9247-y ER - TY - CONF T1 - Workflow-enhanced conformational analysis of guanidine zinc complexes via a science gateway T2 - HealthGrid Applications and Technologies Meet Science Gateways for Life Sciences Y1 - 2012 A1 - Herres-Pawlis, Sonja A1 - Birkenheuer, Georg A1 - Brinkmann, André A1 - Gesing, Sandra A1 - Grunzke, Richard A1 - Jäkel, René A1 - Kohlbacher, Oliver A1 - Krüger, Jens A1 - Dos Santos Vieira, Ines JF - HealthGrid Applications and Technologies Meet Science Gateways for Life Sciences PB - IOS Press ER - TY - JOUR T1 - Automatically Identifying and Annotating Mouse Embryo Gene Expression Patterns JF - Bioinformatics Y1 - 2011 A1 - Liangxiu Han A1 - van Hemert, Jano A1 - Richard Baldock KW - classification KW - e-Science AB - Motivation: Deciphering the regulatory and developmental mechanisms for multicellular organisms requires detailed knowledge of gene interactions and gene expressions. The availability of large datasets with both spatial and ontological annotation of the spatio-temporal patterns of gene-expression in mouse embryo provides a powerful resource to discover the biological function of embryo organisation. Ontological annotation of gene expressions consists of labelling images with terms from the anatomy ontology for mouse development. If the spatial genes of an anatomical component are expressed in an image, the image is then tagged with a term of that anatomical component. The current annotation is done manually by domain experts, which is both time consuming and costly. In addition, the level of detail is variable and inevitably, errors arise from the tedious nature of the task. In this paper, we present a new method to automatically identify and annotate gene expression patterns in the mouse embryo with anatomical terms. Results: The method takes images from in situ hybridisation studies and the ontology for the developing mouse embryo, it then combines machine learning and image processing techniques to produce classifiers that automatically identify and annotate gene expression patterns in these images.We evaluate our method on image data from the EURExpress-II study where we use it to automatically classify nine anatomical terms: humerus, handplate, fibula, tibia, femur, ribs, petrous part, scapula and head mesenchyme. The accuracy of our method lies between 70–80% with few exceptions. Conclusions: We show that other known methods have lower classification performance than ours. We have investigated the images misclassified by our method and found several cases where the original annotation was not correct. This shows our method is robust against this kind of noise. Availability: The annotation result and the experimental dataset in the paper can be freely accessed at http://www2.docm.mmu.ac.uk/STAFF/L.Han/geneannotation/ Contact: l.han@mmu.ac.uk, j.vanhemert@ed.ac.uk and Richard.Baldock@hgu.mrc.ac.uk VL - 27 UR - http://bioinformatics.oxfordjournals.org/content/early/2011/02/25/bioinformatics.btr105.abstract ER - TY - JOUR T1 - Generating web-based user interfaces for computational science JF - Concurrency and Computation: Practice and Experience Y1 - 2011 A1 - van Hemert, J. A1 - Koetsier, J. A1 - Torterolo, L. A1 - Porro, I. A1 - Melato, M. A1 - Barbera, R. AB - Scientific gateways in the form of web portals are becoming the popular approach to share knowledge and resources around a topic in a community of researchers. Unfortunately, the development of web portals is expensive and requires specialists skills. Commercial and more generic web portals have a much larger user base and can afford this kind of development. Here we present two solutions that address this problem in the area of portals for scientific computing; both take the same approach. The whole process of designing, delivering and maintaining a portal can be made more cost-effective by generating a portal from a description rather than programming in the traditional sense. We show four successful use cases to show how this process works and the results it can deliver. PB - Wiley VL - 23 ER - TY - JOUR T1 - A Generic Parallel Processing Model for Facilitating Data Mining and Integration JF - Parallel Computing Y1 - 2011 A1 - Liangxiu Han A1 - Chee Sun Liew A1 - van Hemert, Jano A1 - Malcolm Atkinson KW - Data Mining and Data Integration (DMI) KW - Life Sciences KW - OGSA-DAI KW - Parallelism KW - Pipeline Streaming KW - workflow AB - To facilitate Data Mining and Integration (DMI) processes in a generic way, we investigate a parallel pipeline streaming model. We model a DMI task as a streaming data-flow graph: a directed acyclic graph (DAG) of Processing Elements PEs. The composition mechanism links PEs via data streams, which may be in memory, buffered via disks or inter-computer data-flows. This makes it possible to build arbitrary DAGs with pipelining and both data and task parallelisms, which provides room for performance enhancement. We have applied this approach to a real DMI case in the Life Sciences and implemented a prototype. To demonstrate feasibility of the modelled DMI task and assess the efficiency of the prototype, we have also built a performance evaluation model. The experimental evaluation results show that a linear speedup has been achieved with the increase of the number of distributed computing nodes in this case study. PB - Elsevier VL - 37 IS - 3 ER - TY - CONF T1 - Granular Security for a Science Gateway in Structural Bioinformatics T2 - Proceedings of the International Workshop on Science Gateways for Life Sciences (IWSG-Life 2011) Y1 - 2011 A1 - Gesing, Sandra A1 - Grunzke, Richard A1 - Balaskó, Ákos A1 - Birkenheuer, Georg A1 - Blunk, Dirk A1 - Breuers, Sebastian A1 - Brinkmann, André A1 - Fels, Gregor A1 - Herres-Pawlis, Sonja A1 - Kacsuk, Peter A1 - Kozlovszky, Miklos A1 - Krüger, Jens A1 - Packschies, Lars A1 - Schäfer, Patrick A1 - Schuller, Bernd A1 - Schuster, Johannes A1 - Steinke, Thomas A1 - Szikszay Fabri, Anna A1 - Wewior, Martin A1 - Müller-Pfefferkorn, Ralph A1 - Kohlbacher, Oliver JF - Proceedings of the International Workshop on Science Gateways for Life Sciences (IWSG-Life 2011) PB - CEUR Workshop Proceedings ER - TY - JOUR T1 - Managing dynamic enterprise and urgent workloads on clouds using layered queuing and historical performance models JF - Simulation Modelling Practice and Theory Y1 - 2011 A1 - David A. Bacigalupo A1 - van Hemert, Jano I. A1 - Xiaoyu Chen A1 - Asif Usmani A1 - Adam P. Chester A1 - Ligang He A1 - Donna N. Dillenberger A1 - Gary B. Wills A1 - Lester Gilbert A1 - Stephen A. Jarvis KW - e-Science AB - The automatic allocation of enterprise workload to resources can be enhanced by being able to make what–if response time predictions whilst different allocations are being considered. We experimentally investigate an historical and a layered queuing performance model and show how they can provide a good level of support for a dynamic-urgent cloud environment. Using this we define, implement and experimentally investigate the effectiveness of a prediction-based cloud workload and resource management algorithm. Based on these experimental analyses we: (i) comparatively evaluate the layered queuing and historical techniques; (ii) evaluate the effectiveness of the management algorithm in different operating scenarios; and (iii) provide guidance on using prediction-based workload and resource management. VL - 19 ER - TY - JOUR T1 - Performance database: capturing data for optimizing distributed streaming workflows JF - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences Y1 - 2011 A1 - Chee Sun Liew A1 - Atkinson, Malcolm P. A1 - Radoslaw Ostrowski A1 - Murray Cole A1 - van Hemert, Jano I. A1 - Liangxiu Han KW - measurement framework KW - performance data KW - streaming workflows AB - The performance database (PDB) stores performance-related data gathered during workflow enactment. We argue that by carefully understanding and manipulating this data, we can improve efficiency when enacting workflows. This paper describes the rationale behind the PDB, and proposes a systematic way to implement it. The prototype is built as part of the Advanced Data Mining and Integration Research for Europe project. We use workflows from real-world experiments to demonstrate the usage of PDB. VL - 369 IS - 1949 ER - TY - CONF T1 - RapidBrain: Developing a Portal for Brain Research Imaging T2 - All Hands Meeting 2011, York Y1 - 2011 A1 - Kenton D'Mellow A1 - Rodríguez, David A1 - Carpenter, Trevor A1 - Jos Koetsier A1 - Dominic Job A1 - van Hemert, Jano A1 - Wardlaw, Joanna A1 - Fan Zhu AB - Brain imaging researchers execute complex multistep workflows in their computational analysis. Those workflows often include applications that have very different user interfaces and sometimes use different data formats. A good example is the brain perfusion quantification workflow used at the BRIC (Brain Research Imaging Centre) in Edinburgh. Rapid provides an easy method for creating portlets for computational jobs, and at the same it is extensible. We have exploited this extensibility with additions that stretch the functionality beyond the original limits. These changes can be used by other projects to create their own portals, but it should be noted that the development of such portals involve a greater effort than the required in the regular use of Rapid for creating portlets. In our case it has been used to provide a user-friendly interface for perfusion analysis that covers from volume JF - All Hands Meeting 2011, York CY - York ER - TY - CONF T1 - A Science Gateway for Molecular Simulations T2 - EGI User Forum 2011 Y1 - 2011 A1 - Gesing, Sandra A1 - Kacsuk, Peter A1 - Kozlovszky, Miklos A1 - Birkenheuer, Georg A1 - Blunk, Dirk A1 - Breuers, Sebastian A1 - Brinkmann, André A1 - Fels, Gregor A1 - Grunzke, Richard A1 - Herres-Pawlis, Sonja A1 - Krüger, Jens A1 - Packschies, Lars A1 - Müller-Pfefferkorn, Ralph A1 - Schäfer, Patrick A1 - Steinke, Thomas A1 - Szikszay Fabri, Anna A1 - Warzecha, Klaus A1 - Wewior, Martin A1 - Kohlbacher, Oliver JF - EGI User Forum 2011 SN - 978 90 816927 1 7 ER - TY - JOUR T1 - Special Issue: Portals for life sciences---Providing intuitive access to bioinformatic tools JF - Concurrency and Computation: Practice and Experience Y1 - 2011 A1 - Gesing, Sandra A1 - van Hemert, J. A1 - Kacsuk, P. A1 - Kohlbacher, O. AB - The topic ‘Portals for life sciences’ includes various research fields, on the one hand many different topics out of life sciences, e.g. mass spectrometry, on the other hand portal technologies and different aspects of computer science, such as usability of user interfaces and security of systems. The main aspect about portals is to simplify the user’s interaction with computational resources that are concerted to a supported application domain. PB - Wiley VL - 23 IS - 23 ER - TY - JOUR T1 - A user-friendly web portal for T-Coffee on supercomputers JF - BMC Bioinformatics Y1 - 2011 A1 - J. Rius A1 - F. Cores A1 - F. Solsona A1 - van Hemert, J. I. A1 - Koetsier, J. A1 - C. Notredame KW - e-Science KW - portal KW - rapid AB - Background Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is to reduce the execution time of the large-scale sequence alignments. It can be run on distributed memory clusters allowing users to align data sets consisting of hundreds of proteins within a reasonable time. However, most of the potential users of this tool are not familiar with the use of grids or supercomputers. Results In this paper we show how PTC can be easily deployed and controlled on a super computer architecture using a web portal developed using Rapid. Rapid is a tool for efficiently generating standardized portlets for a wide range of applications and the approach described here is generic enough to be applied to other applications, or to deploy PTC on different HPC environments. Conclusions The PTC portal allows users to upload a large number of sequences to be aligned by the parallel version of TC that cannot be aligned by a single machine due to memory and execution time constraints. The web portal provides a user-friendly solution. VL - 12 UR - http://www.biomedcentral.com/1471-2105/12/150 ER - TY - JOUR T1 - Validation and mismatch repair of workflows through typed data streams JF - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences Y1 - 2011 A1 - Yaikhom, Gagarine A1 - Malcolm Atkinson A1 - van Hemert, Jano A1 - Oscar Corcho A1 - Krause, Amy AB - The type system of a language guarantees that all of the operations on a set of data comply with the rules and conditions set by the language. While language typing is a fundamental requirement for any programming language, the typing of data that flow between processing elements within a workflow is currently being treated as optional. In this paper, we introduce a three-level type system for typing workflow data streams. These types are parts of the Data Intensive System Process Engineering Language programming language, which empowers users with the ability to validate the connections inside a workflow composition, and apply appropriate data type conversions when necessary. Furthermore, this system enables the enactment engine in carrying out type-directed workflow optimizations. VL - 369 IS - 1949 ER - TY - CONF T1 - Accelerating Data-Intensive Applications: a Cloud Computing Approach Image Pattern Recognition Tasks T2 - The Fourth International Conference on Advanced Engineering Computing and Applications in Sciences Y1 - 2010 A1 - Han, L A1 - Saengngam, T. A1 - van Hemert, J. JF - The Fourth International Conference on Advanced Engineering Computing and Applications in Sciences ER - TY - JOUR T1 - Correcting for intra-experiment variation in Illumina BeadChip data is necessary to generate robust gene-expression profiles JF - BMC Genomics Y1 - 2010 A1 - R. R. Kitchen A1 - V. S. Sabine A1 - A. H. Sims A1 - E. J. Macaskill A1 - L. Renshaw A1 - J. S. Thomas A1 - van Hemert, J. I. A1 - J. M. Dixon A1 - J. M. S. Bartlett AB - Background Microarray technology is a popular means of producing whole genome transcriptional profiles, however high cost and scarcity of mRNA has led many studies to be conducted based on the analysis of single samples. We exploit the design of the Illumina platform, specifically multiple arrays on each chip, to evaluate intra-experiment technical variation using repeated hybridisations of universal human reference RNA (UHRR) and duplicate hybridisations of primary breast tumour samples from a clinical study. Results A clear batch-specific bias was detected in the measured expressions of both the UHRR and clinical samples. This bias was found to persist following standard microarray normalisation techniques. However, when mean-centering or empirical Bayes batch-correction methods (ComBat) were applied to the data, inter-batch variation in the UHRR and clinical samples were greatly reduced. Correlation between replicate UHRR samples improved by two orders of magnitude following batch-correction using ComBat (ranging from 0.9833-0.9991 to 0.9997-0.9999) and increased the consistency of the gene-lists from the duplicate clinical samples, from 11.6% in quantile normalised data to 66.4% in batch-corrected data. The use of UHRR as an inter-batch calibrator provided a small additional benefit when used in conjunction with ComBat, further increasing the agreement between the two gene-lists, up to 74.1%. Conclusion In the interests of practicalities and cost, these results suggest that single samples can generate reliable data, but only after careful compensation for technical bias in the experiment. We recommend that investigators appreciate the propensity for such variation in the design stages of a microarray experiment and that the use of suitable correction methods become routine during the statistical analysis of the data. VL - 11 UR - http://www.biomedcentral.com/1471-2164/11/134 IS - 134 ER - TY - RPRT T1 - Data-Intensive Research Workshop (15-19 March 2010) Report Y1 - 2010 A1 - Malcolm Atkinson A1 - Roure, David De A1 - van Hemert, Jano A1 - Shantenu Jha A1 - Ruth McNally A1 - Robert Mann A1 - Stratis Viglas A1 - Chris Williams KW - Data-intensive Computing KW - Data-Intensive Machines KW - Machine Learning KW - Scientific Databases AB - We met at the National e-Science Institute in Edinburgh on 15-19 March 2010 to develop our understanding of DIR. Approximately 100 participants (see Appendix A) worked together to develop their own understanding, and we are offering this report as the first step in communicating that to a wider community. We present this in turns of our developing/emerging understanding of "What is DIR?" and "Why it is important?'". We then review the status of the field, report what the workshop achieved and what remains as open questions. JF - National e-Science Centre PB - Data-Intensive Research Group, School of Informatics, University of Edinburgh CY - Edinburgh ER - TY - CHAP T1 - Exploiting P2P and Grid Computing Technologies for Resource Sharing to support High Performance Distributed System T2 - Handbook of Research on P2P and Grid Systems for Service-Oriented Computing: Models, Methodologies and Applications Y1 - 2010 A1 - Liangxiu Han ED - Nick Antonopoulos ED - Georgios Exarchakos ED - Maozhen Li ED - Antonio Liottac JF - Handbook of Research on P2P and Grid Systems for Service-Oriented Computing: Models, Methodologies and Applications PB - IGI Global publishing VL - 1 ER - TY - Generic T1 - Federated Enactment of Workflow Patterns T2 - Lecture Notes in Computer Science Y1 - 2010 A1 - Yaikhom, Gagarine A1 - Liew, Chee A1 - Liangxiu Han A1 - van Hemert, Jano A1 - Malcolm Atkinson A1 - Krause, Amy ED - D’Ambra, Pasqua ED - Guarracino, Mario ED - Talia, Domenico AB - In this paper we address two research questions concerning workflows: 1) how do we abstract and catalogue recurring workflow patterns?; and 2) how do we facilitate optimisation of the mapping from workflow patterns to actual resources at runtime? Our aim here is to explore techniques that are applicable to large-scale workflow compositions, where the resources could change dynamically during the lifetime of an application. We achieve this by introducing a registry-based mechanism where pattern abstractions are catalogued and stored. In conjunction with an enactment engine, which communicates with this registry, concrete computational implementations and resources are assigned to these patterns, conditional to the execution parameters. Using a data mining application from the life sciences, we demonstrate this new approach. JF - Lecture Notes in Computer Science PB - Springer Berlin / Heidelberg VL - 6271 UR - http://dx.doi.org/10.1007/978-3-642-15277-1_31 N1 - 10.1007/978-3-642-15277-1_31 ER - TY - CONF T1 - Grid-Workflows in Molecular Science T2 - Software Engineering 2010, Grid Workflow Workshop Y1 - 2010 A1 - Birkenheuer, Georg A1 - Breuers, Sebastian A1 - Brinkmann, André A1 - Blunk, Dirk A1 - Fels, Gregor A1 - Gesing, Sandra A1 - Herres-Pawlis, Sonja A1 - Kohlbacher, Oliver A1 - Krüger, Jens A1 - Packschies, Lars JF - Software Engineering 2010, Grid Workflow Workshop PB - GI-Edition - Lecture Notes in Informatics (LNI) ER - TY - JOUR T1 - Integrating distributed data sources with OGSA--DAI DQP and Views JF - Philosophical Transactions A Y1 - 2010 A1 - Dobrzelecki, B. A1 - Krause, A. A1 - Hume, A. C. A1 - Grant, A. A1 - Antonioletti, M. A1 - Alemu, T. Y. A1 - Atkinson, M. A1 - Jackson, M. A1 - Theocharopoulos, E. AB - OGSA-DAI (Open Grid Services Architecture Data Access and Integration) is a framework for building distributed data access and integration systems. Until recently, it lacked the built-in functionality that would allow easy creation of federations of distributed data sources. The latest release of the OGSA-DAI framework introduced the OGSA-DAI DQP (Distributed Query Processing) resource. The new resource encapsulates a distributed query processor, that is able to orchestrate distributed data sources when answering declarative user queries. The query processor has many extensibility points, making it easy to customize. We have also introduced a new OGSA-DAI Views resource that provides a flexible method for defining views over relational data. The interoperability of the two new resources, together with the flexibility of the OGSA-DAI framework, allows the building of highly customized data integration solutions. VL - 368 ER - TY - CHAP T1 - Molecular Orbital Calculations of Inorganic Compounds T2 - Inorganic Experiments Y1 - 2010 A1 - C. A. Morrison A1 - N. Robertson A1 - Turner, A. A1 - van Hemert, J. A1 - Koetsier, J. ED - J. Derek Woollins JF - Inorganic Experiments PB - Wiley-VCH SN - 978-3527292530 ER - TY - CONF T1 - The MoSGrid Gaussian Portlet – Technologies for the Implementation of Portlets for Molecular Simulations T2 - Proceedings of the International Workshop on Science Gateways (IWSG10) Y1 - 2010 A1 - Wewior, Martin A1 - Packschies, Lars A1 - Blunk, Dirk A1 - Wickeroth, D. A1 - Warzecha, Klaus A1 - Herres-Pawlis, Sonja A1 - Gesing, Sandra A1 - Breuers, Sebastian A1 - Krüger, Jens A1 - Birkenheuer, Georg A1 - Lang, Ulrich ED - Barbera, Roberto ED - Andronico, Giuseppe ED - La Rocca, Giuseppe JF - Proceedings of the International Workshop on Science Gateways (IWSG10) PB - Consorzio COMETA ER - TY - JOUR T1 - An open source toolkit for medical imaging de-identification JF - European Radiology Y1 - 2010 A1 - Rodríguez, David A1 - Carpenter, Trevor K. A1 - van Hemert, Jano I. A1 - Wardlaw, Joanna M. KW - Anonymisation KW - Data Protection Act (DPA) KW - De-identification KW - Digital Imaging and Communications in Medicine (DICOM) KW - Privacy policies KW - Pseudonymisation KW - Toolkit AB - Objective Medical imaging acquired for clinical purposes can have several legitimate secondary uses in research projects and teaching libraries. No commonly accepted solution for anonymising these images exists because the amount of personal data that should be preserved varies case by case. Our objective is to provide a flexible mechanism for anonymising Digital Imaging and Communications in Medicine (DICOM) data that meets the requirements for deployment in multicentre trials. Methods We reviewed our current de-identification practices and defined the relevant use cases to extract the requirements for the de-identification process. We then used these requirements in the design and implementation of the toolkit. Finally, we tested the toolkit taking as a reference those requirements, including a multicentre deployment. Results The toolkit successfully anonymised DICOM data from various sources. Furthermore, it was shown that it could forward anonymous data to remote destinations, remove burned-in annotations, and add tracking information to the header. The toolkit also implements the DICOM standard confidentiality mechanism. Conclusion A DICOM de-identification toolkit that facilitates the enforcement of privacy policies was developed. It is highly extensible, provides the necessary flexibility to account for different de-identification requirements and has a low adoption barrier for new users. VL - 20 UR - http://www.springerlink.com/content/j20844338623m167/ IS - 8 ER - TY - CONF T1 - Resource management of enterprise cloud systems using layered queuing and historical performance models T2 - IEEE International Symposium on Parallel Distributed Processing Y1 - 2010 A1 - Bacigalupo, D. A. A1 - van Hemert, J. A1 - Usmani, A. A1 - Dillenberger, D. N. A1 - Wills, G. B. A1 - Jarvis, S. A. KW - e-Science AB - The automatic allocation of enterprise workload to resources can be enhanced by being able to make `what-if' response time predictions, whilst different allocations are being considered. It is important to quantitatively compare the effectiveness of different prediction techniques for use in cloud infrastructures. To help make the comparison of relevance to a wide range of possible cloud environments it is useful to consider the following. 1.) urgent cloud customers such as the emergency services that can demand cloud resources at short notice (e.g. for our FireGrid emergency response software). 2.) dynamic enterprise systems, that must rapidly adapt to frequent changes in workload, system configuration and/or available cloud servers. 3.) The use of the predictions in a coordinated manner by both the cloud infrastructure and cloud customer management systems. 4.) A broad range of criteria for evaluating each technique. However, there have been no previous comparisons meeting these requirements. This paper, meeting the above requirements, quantitatively compares the layered queuing and (\^A¿HYDRA\^A¿) historical techniques - including our initial thoughts on how they could be combined. Supporting results and experiments include the following: i.) defining, investigating and hence providing guidelines on the use of a historical and layered queuing model; ii.) using these guidelines showing that both techniques can make low overhead and typically over 70% accurate predictions, for new server architectures for which only a small number of benchmarks have been run; and iii.) defining and investigating tuning a prediction-based cloud workload and resource management algorithm. JF - IEEE International Symposium on Parallel Distributed Processing ER - TY - CONF T1 - TOPP goes Rapid T2 - Cluster Computing and the Grid, IEEE International Symposium on Y1 - 2010 A1 - Gesing, Sandra A1 - van Hemert, Jano A1 - Jos Koetsier A1 - Bertsch, Andreas A1 - Kohlbacher, Oliver AB - Proteomics, the study of all the proteins contained in a particular sample, e.g., a cell, is a key technology in current biomedical research. The complexity and volume of proteomics data sets produced by mass spectrometric methods clearly suggests the use of grid-based high-performance computing for analysis. TOPP and OpenMS are open-source packages for proteomics data analysis; however, they do not provide support for Grid computing. In this work we present a portal interface for high-throughput data analysis with TOPP. The portal is based on Rapid, a tool for efficiently generating standardized portlets for a wide range of applications. The web-based interface allows the creation and editing of user-defined pipelines and their execution and monitoring on a Grid infrastructure. The portal also supports several file transfer protocols for data staging. It thus provides a simple and complete solution to high-throughput proteomics data analysis for inexperienced users through a convenient portal interface. JF - Cluster Computing and the Grid, IEEE International Symposium on PB - IEEE Computer Society CY - Los Alamitos, CA, USA SN - 978-0-7695-4039-9 ER - TY - CONF T1 - Towards Optimising Distributed Data Streaming Graphs using Parallel Streams T2 - Data Intensive Distributed Computing (DIDC'10), in conjunction with the 19th International Symposium on High Performance Distributed Computing Y1 - 2010 A1 - Chee Sun Liew A1 - Atkinson, Malcolm P. A1 - van Hemert, Jano A1 - Liangxiu Han KW - Data-intensive Computing KW - Distributed Computing KW - Optimisation KW - Parallel Stream KW - Scientific Workflows AB - Modern scientific collaborations have opened up the opportunity of solving complex problems that involve multi- disciplinary expertise and large-scale computational experiments. These experiments usually involve large amounts of data that are located in distributed data repositories running various software systems, and managed by different organisations. A common strategy to make the experiments more manageable is executing the processing steps as a workflow. In this paper, we look into the implementation of fine-grained data-flow between computational elements in a scientific workflow as streams. We model the distributed computation as a directed acyclic graph where the nodes represent the processing elements that incrementally implement specific subtasks. The processing elements are connected in a pipelined streaming manner, which allows task executions to overlap. We further optimise the execution by splitting pipelines across processes and by introducing extra parallel streams. We identify performance metrics and design a measurement tool to evaluate each enactment. We conducted ex- periments to evaluate our optimisation strategies with a real world problem in the Life Sciences—EURExpress-II. The paper presents our distributed data-handling model, the optimisation and instrumentation strategies and the evaluation experiments. We demonstrate linear speed up and argue that this use of data-streaming to enable both overlapped pipeline and parallelised enactment is a generally applicable optimisation strategy. JF - Data Intensive Distributed Computing (DIDC'10), in conjunction with the 19th International Symposium on High Performance Distributed Computing PB - ACM CY - Chicago, Illinois UR - http://www.cct.lsu.edu/~kosar/didc10/index.php ER - TY - CONF T1 - Understanding TSP Difficulty by Learning from Evolved Instances T2 - Lecture Notes in Computer Science Y1 - 2010 A1 - Smith-Miles, Kate A1 - van Hemert, Jano A1 - Lim, Xin ED - Blum, Christian ED - Battiti, Roberto AB - Whether the goal is performance prediction, or insights into the relationships between algorithm performance and instance characteristics, a comprehensive set of meta-data from which relationships can be learned is needed. This paper provides a methodology to determine if the meta-data is sufficient, and demonstrates the critical role played by instance generation methods. Instances of the Travelling Salesman Problem (TSP) are evolved using an evolutionary algorithm to produce distinct classes of instances that are intentionally easy or hard for certain algorithms. A comprehensive set of features is used to characterise instances of the TSP, and the impact of these features on difficulty for each algorithm is analysed. Finally, performance predictions are achieved with high accuracy on unseen instances for predicting search effort as well as identifying the algorithm likely to perform best. JF - Lecture Notes in Computer Science PB - Springer Berlin / Heidelberg VL - 6073 UR - http://dx.doi.org/10.1007/978-3-642-13800-3_29 N1 - 10.1007/978-3-642-13800-3_29 ER - TY - RPRT T1 - ADMIRE D1.5 – Report defining an iteration of the model and language: PM3 and DL3 Y1 - 2009 A1 - Peter Brezany A1 - Ivan Janciak A1 - Alexander Woehrer A1 - Carlos Buil Aranda A1 - Malcolm Atkinson A1 - van Hemert, Jano AB - This document is the third deliverable to report on the progress of the model, language and ontology research conducted within Workpackage 1 of the ADMIRE project. Significant progress has been made on each of the above areas. The new results that we achieved are recorded against the targets defined for project month 18 and are reported in four sections of this document PB - ADMIRE project UR - http://www.admire-project.eu/docs/ADMIRE-D1.5-model-language-ontology.pdf ER - TY - CONF T1 - Adoption of e-Infrastructure Services: inhibitors, enablers and opportunities T2 - 5th International Conference on e-Social Science Y1 - 2009 A1 - Voss, A. A1 - Asgari-Targhi, M. A1 - Procter, R. A1 - Halfpenny, P. A1 - Fragkouli, E. A1 - Anderson, S. A1 - Hughes, L. A1 - Fergusson, D. A1 - Vander Meer, E. A1 - Atkinson, M. AB - Based on more than 100 interviews with respondents from the academic community and information services, we present findings from our study of inhibitors and enablers of adoption of e-Infrastructure services for research. We discuss issues raised and potential ways of addressing them. JF - 5th International Conference on e-Social Science CY - Maternushaus, Cologne ER - TY - CONF T1 - Advanced Data Mining and Integration Research for Europe T2 - All Hands Meeting 2009 Y1 - 2009 A1 - Atkinson, M. A1 - Brezany, P. A1 - Corcho, O. A1 - Han, L A1 - van Hemert, J. A1 - Hluchy, L. A1 - Hume, A. A1 - Janciak, I. A1 - Krause, A. A1 - Snelling, D. A1 - Wöhrer, A. AB - There is a rapidly growing wealth of data [1]. The number of sources of data is increasing, while, at the same time, the diversity, complexity and scale of these data resources are also increasing dramatically. This cornucopia of data o ers much potential; a combinatorial explosion of opportunities for knowledge discovery, improved decisions and better policies. Today, most of these opportunities are not realised because composing data from multiple sources and extracting information is too dicult. Every business, organisation and government faces problems that can only be addressed successfully if we improve our techniques for exploiting the data we gather. JF - All Hands Meeting 2009 CY - Oxford ER - TY - CONF T1 - Automating Gene Expression Annotation for Mouse Embryo T2 - Lecture Notes in Computer Science (Advanced Data Mining and Applications, 5th International Conference) Y1 - 2009 A1 - Liangxiu Han A1 - van Hemert, Jano A1 - Richard Baldock A1 - Atkinson, Malcolm P. ED - Ronghuai Huang ED - Qiang Yang ED - Jian Pei ED - et al JF - Lecture Notes in Computer Science (Advanced Data Mining and Applications, 5th International Conference) PB - Springer VL - LNAI 5678 ER - TY - JOUR T1 - The Circulate Architecture: Avoiding Workflow Bottlenecks Caused By Centralised Orchestration JF - Cluster Computing Y1 - 2009 A1 - Barker, A. A1 - Weissman, J. A1 - van Hemert, J. I. KW - grid computing KW - workflow VL - 12 UR - http://www.springerlink.com/content/080q5857711w2054/?p=824749739c6a432ea95a0c3b59f4025f&pi=1 ER - TY - CONF T1 - A Distributed Architecture for Data Mining and Integration T2 - Data-Aware Distributed Computing (DADC'09), in conjunction with the 18th International Symposium on High Performance Distributed Computing Y1 - 2009 A1 - Atkinson, Malcolm P. A1 - van Hemert, Jano A1 - Liangxiu Han A1 - Ally Hume A1 - Chee Sun Liew AB - This paper presents the rationale for a new architecture to support a significant increase in the scale of data integration and data mining. It proposes the composition into one framework of (1) data mining and (2) data access and integration. We name the combined activity “DMI”. It supports enactment of DMI processes across heterogeneous and distributed data resources and data mining services. It posits that a useful division can be made between the facilities established to support the definition of DMI processes and the computational infrastructure provided to enact DMI processes. Communication between those two divisions is restricted to requests submitted to gateway services in a canonical DMI language. Larger-scale processes are enabled by incremental refinement of DMI-process definitions often by recomposition of lower-level definitions. Autonomous types and descriptions which will support detection of inconsistencies and semi-automatic insertion of adaptations.These architectural ideas are being evaluated in a feasibility study that involves an application scenario and representatives of the community. JF - Data-Aware Distributed Computing (DADC'09), in conjunction with the 18th International Symposium on High Performance Distributed Computing PB - ACM ER - TY - RPRT T1 - An e-Infrastructure for Collaborative Research in Human Embryo Development Y1 - 2009 A1 - Barker, Adam A1 - van Hemert, Jano I. A1 - Baldock, Richard A. A1 - Atkinson, Malcolm P. AB - Within the context of the EU Design Study Developmental Gene Expression Map, we identify a set of challenges when facilitating collaborative research on early human embryo development. These challenges bring forth requirements, for which we have identified solutions and technology. We summarise our solutions and demonstrate how they integrate to form an e-infrastructure to support collaborative research in this area of developmental biology. UR - http://arxiv.org/pdf/0901.2310v1 ER - TY - CONF T1 - An E-infrastructure to Support Collaborative Embryo Research T2 - Cluster Computing and the Grid Y1 - 2009 A1 - Barker, Adam A1 - van Hemert, Jano I. A1 - Baldock, Richard A. A1 - Atkinson, Malcolm P. JF - Cluster Computing and the Grid PB - IEEE Computer Society SN - 978-0-7695-3622-4 ER - TY - CHAP T1 - Exploiting Fruitful Regions in Dynamic Routing using Evolutionary Computation T2 - Studies in Computational Intelligence Y1 - 2009 A1 - van Hemert, J. I. A1 - la Poutré, J. A. ED - Pereira Babtista, F. ED - Tavares, J. JF - Studies in Computational Intelligence PB - Springer VL - 161 SN - 978-3-540-85151-6 N1 - Awaiting publication (due October 2008) ER - TY - JOUR T1 - Giving Computational Science a Friendly Face JF - Zero-In Y1 - 2009 A1 - van Hemert, J. I. A1 - Koetsier, J. AB - Today, most researchers from any discipline will successfully use web-based e-commerce systems to book flights to attend their conferences. But when these same researchers are confronted with compute-intensive problems, they cannot expect elaborate web-based systems to enable their domain-specific tasks. VL - 1 UR - http://www.beliefproject.org/zero-in/zero-in-third-edition/zero-in-issue-3 IS - 3 ER - TY - CONF T1 - A model of social collaboration in Molecular Biology knowledge bases T2 - Proceedings of the 6th Conference of the European Social Simulation Association (ESSA'09) Y1 - 2009 A1 - De Ferrari, Luna A1 - Stuart Aitken A1 - van Hemert, Jano A1 - Goryanin, Igor AB - Manual annotation of biological data cannot keep up with data production. Open annotation models using wikis have been proposed to address this problem. In this empirical study we analyse 36 years of knowledge collection by 738 authors in two Molecular Biology wikis (EcoliWiki and WikiPathways) and two knowledge bases (OMIM and Reactome). We first investigate authorship metrics (authors per entry and edits per author) which are power-law distributed in Wikipedia and we find they are heavy-tailed in these four systems too. We also find surprising similarities between the open (editing open to everyone) and the closed systems (expert curators only). Secondly, to discriminate between driving forces in the measured distributions, we simulate the curation process and find that knowledge overlap among authors can drive the number of authors per entry, while the time the users spend on the knowledge base can drive the number of contributions per author. JF - Proceedings of the 6th Conference of the European Social Simulation Association (ESSA'09) PB - European Social Simulation Association ER - TY - JOUR T1 - The performance model of dynamic Virtual Organization (VO) formations within grid computing context JF - Chaos, Solitons & Fractals Y1 - 2009 A1 - Liangxiu Han KW - complex network KW - graph theory KW - grid computing KW - virtual organization formation PB - Elsevier Science VL - 40 IS - 4 N1 - In press ER - TY - CONF T1 - Portals for Life Sciences—a Brief Introduction T2 - Proceedings of the IWPLS09 International Workshop on Portals for Life Sciences Y1 - 2009 A1 - Gesing, Sandra A1 - Kohlbacher, O. A1 - van Hemert, J. I. AB - The topic ”‘Portals for Life Sciences”’ includes various research fields, on the one hand many different topics out of life sciences, e.g. mass spectrometry, on the other hand portal technologies and different aspects of computer science, such as usability of user interfaces and security of systems. The main aspect about portals is to simplify the user’s interaction with computational resources which are concer- ted to a supported application domain. JF - Proceedings of the IWPLS09 International Workshop on Portals for Life Sciences T3 - CEUR Workshop Proceedings UR - http://ceur-ws.org/Vol-513/paper01.pdf ER - TY - Generic T1 - Proceedings of the 1st International Workshop on Portals for Life Sciences T2 - IWPLS09 International Workshop on Portals for Life Sciences Y1 - 2009 A1 - Gesing, Sandra A1 - van Hemert, Jano I. JF - IWPLS09 International Workshop on Portals for Life Sciences T3 - CEUR Workshop Proceedings CY - e-Science Institute, Edinburgh, UK UR - http://ceur-ws.org/Vol-513 ER - TY - CONF T1 - Rapid chemistry portals through engaging researchers T2 - Fifth IEEE International Conference on e-Science Y1 - 2009 A1 - Koetsier, J. A1 - Turner, A. A1 - Richardson, P. A1 - van Hemert, J. I. ED - Trefethen, A ED - De Roure, D AB - In this study, we apply a methodology for rapid development of portlets for scientific computing to the domain of computational chemistry. We report results in terms of the portals delivered, the changes made to our methodology and the experience gained in terms of interaction with domain-specialists. Our major contributions are: several web portals for teaching and research in computational chemistry; a successful transition to having our development tool used by the domain specialist as opposed by us, the developers; and an updated version of our methodology and technology for rapid development of portlets for computational science, which is free for anyone to pick up and use. JF - Fifth IEEE International Conference on e-Science CY - Oxford, UK ER - TY - CONF T1 - Rapid development of computational science portals T2 - Proceedings of the IWPLS09 International Workshop on Portals for Life Sciences Y1 - 2009 A1 - Koetsier, J. A1 - van Hemert, J. I. ED - Gesing, S. ED - van Hemert, J. I. KW - portal JF - Proceedings of the IWPLS09 International Workshop on Portals for Life Sciences T3 - CEUR Workshop Proceedings PB - e-Science Institute CY - Edinburgh UR - http://ceur-ws.org/Vol-513/paper05.pdf ER - TY - JOUR T1 - Simultaneous alignment of short reads against multiple genomes JF - Genome Biol Y1 - 2009 A1 - Schneeberger, Korbinian A1 - Hagmann, Jörg A1 - Ossowski, Stephan A1 - Warthmann, Norman A1 - Gesing, Sandra A1 - Kohlbacher, Oliver A1 - Weigel, Detlef VL - 10 UR - http://www.biomedsearch.com/nih/Simultaneous-alignment-short-reads-against/19761611.html ER - TY - JOUR T1 - A Strategy for Research and Innovation in the Century of Information JF - Prometheus Y1 - 2009 A1 - e-Science Directors’ Forum Strategy Working Group A1 - Atkinson, M. A1 - Britton, D. A1 - Coveney, P. A1 - De Roure, D A1 - Garnett, N. A1 - Geddes, N. A1 - Gurney, R. A1 - Haines, K. A1 - Hughes, L. A1 - Ingram, D. A1 - Jeffreys, P. A1 - Lyon, L. A1 - Osborne, I. A1 - Perrott, P. A1 - Procter. R. A1 - Rusbridge, C. AB - More data will be produced in the next five years than in the entire history of human kind, a digital deluge that marks the beginning of the Century of Information. Through a year‐long consultation with UK researchers, a coherent strategy has been developed, which will nurture Century‐of‐Information Research (CIR); it crystallises the ideas developed by the e‐Science Directors’ Forum Strategy Working Group. This paper is an abridged version of their latest report which can be found at: http://wikis.nesc.ac.uk/escienvoy/Century_of_Information_Research_Strategy which also records the consultation process and the affiliations of the authors. This document is derived from a paper presented at the Oxford e‐Research Conference 2008 and takes into account suggestions made in the ensuing panel discussion. The goals of the CIR Strategy are to facilitate the growth of UK research and innovation that is data and computationally intensive and to develop a new culture of ‘digital‐systems judgement’ that will equip research communities, businesses, government and society as a whole, with the skills essential to compete and prosper in the Century of Information. The CIR Strategy identifies a national requirement for a balanced programme of coordination, research, infrastructure, translational investment and education to empower UK researchers, industry, government and society. The Strategy is designed to deliver an environment which meets the needs of UK researchers so that they can respond agilely to challenges, can create knowledge and skills, and can lead new kinds of research. It is a call to action for those engaged in research, those providing data and computational facilities, those governing research and those shaping education policies. The ultimate aim is to help researchers strengthen the international competitiveness of the UK research base and increase its contribution to the economy. The objectives of the Strategy are to better enable UK researchers across all disciplines to contribute world‐leading fundamental research; to accelerate the translation of research into practice; and to develop improved capabilities, facilities and context for research and innovation. It envisages a culture that is better able to grasp the opportunities provided by the growing wealth of digital information. Computing has, of course, already become a fundamental tool in all research disciplines. The UK e‐Science programme (2001–06)—since emulated internationally—pioneered the invention and use of new research methods, and a new wave of innovations in digital‐information technologies which have enabled them. The Strategy argues that the UK must now harness and leverage its own, plus the now global, investment in digital‐information technology in order to spread the benefits as widely as possible in research, education, industry and government. Implementing the Strategy would deliver the computational infrastructure and its benefits as envisaged in the Science & Innovation Investment Framework 2004–2014 (July 2004), and in the reports developing those proposals. To achieve this, the Strategy proposes the following actions: 1. support the continuous innovation of digital‐information research methods; 2. provide easily used, pervasive and sustained e‐Infrastructure for all research; 3. enlarge the productive research community which exploits the new methods efficiently; 4. generate capacity, propagate knowledge and develop skills via new curricula; and 5. develop coordination mechanisms to improve the opportunities for interdisciplinary research and to make digital‐infrastructure provision more cost effective. To gain the best value for money strategic coordination is required across a broad spectrum of stakeholders. A coherent strategy is essential in order to establish and sustain the UK as an international leader of well‐curated national data assets and computational infrastructure, which is expertly used to shape policy, support decisions, empower researchers and to roll out the results to the wider benefit of society. The value of data as a foundation for wellbeing and a sustainable society must be appreciated; national resources must be more wisely directed to the collection, curation, discovery, widening access, analysis and exploitation of these data. Every researcher must be able to draw on skills, tools and computational resources to develop insights, test hypotheses and translate inventions into productive use, or to extract knowledge in support of governmental decision making. This foundation plus the skills developed will launch significant advances in research, in business, in professional practice and in government with many consequent benefits for UK citizens. The Strategy presented here addresses these complex and interlocking requirements. VL - 27 ER - TY - JOUR T1 - Towards a Virtual Fly Brain JF - Philosophical Transactions A Y1 - 2009 A1 - Armstrong, J. D. A1 - van Hemert, J. I. KW - e-Science AB - Models of the brain that simulate sensory input, behavioural output and information processing in a biologically plausible manner pose significant challenges to both Computer Science and Biology. Here we investigated strategies that could be used to create a model of the insect brain, specifically that of Drosophila melanogaster which is very widely used in laboratory research. The scale of the problem is an order of magnitude above the most complex of the current simulation projects and it is further constrained by the relative sparsity of available electrophysiological recordings from the fly nervous system. However, fly brain research at the anatomical and behavioural level offers some interesting opportunities that could be exploited to create a functional simulation. We propose to exploit these strengths of Drosophila CNS research to focus on a functional model that maps biologically plausible network architecture onto phenotypic data from neuronal inhibition and stimulation studies, leaving aside biophysical modelling of individual neuronal activity for future models until more data is available. VL - 367 UR - http://rsta.royalsocietypublishing.org/content/367/1896/2387.abstract ER - TY - CONF T1 - Using architectural simulation models to aid the design of data intensive application T2 - The Third International Conference on Advanced Engineering Computing and Applications in Sciences (ADVCOMP 2009) Y1 - 2009 A1 - Javier Fernández A1 - Liangxiu Han A1 - Alberto Nuñez A1 - Jesus Carretero A1 - van Hemert, Jano JF - The Third International Conference on Advanced Engineering Computing and Applications in Sciences (ADVCOMP 2009) PB - IEEE Computer Society CY - Sliema, Malta ER - TY - CONF T1 - Using Simulation for Decision Support: Lessons Learned from FireGrid T2 - Proceedings of the 6th International Conference on Information Systems for Crisis Response and Management (ISCRAM 2009) Y1 - 2009 A1 - Gerhard Wickler A1 - George Beckett A1 - Liangxiu Han A1 - Sung Han Koo A1 - Stephen Potter A1 - Gavin Pringle A1 - Austin Tate ED - J. Landgren, U. Nulden ED - B. Van de Walle JF - Proceedings of the 6th International Conference on Information Systems for Crisis Response and Management (ISCRAM 2009) CY - Gothenburg, Sweden ER - TY - JOUR T1 - Using the DCC Lifecycle Model to Curate a Gene Expression Database: A Case Study JF - International Journal of Digital Curation Y1 - 2009 A1 - O’Donoghue, J. A1 - van Hemert, J. I. AB - Developmental Gene Expression Map (DGEMap) is an EU-funded Design Study, which will accelerate an integrated European approach to gene expression in early human development. As part of this design study, we have had to address the challenges and issues raised by the long-term curation of such a resource. As this project is primarily one of data creators, learning about curation, we have been looking at some of the models and tools that are already available in the digital curation field in order to inform our thinking on how we should proceed with curating DGEMap. This has led us to uncover a wide range of resources for data creators and curators alike. Here we will discuss the future curation of DGEMap as a case study. We believe our experience could be instructive to other projects looking to improve the curation and management of their data. PB - UKOLN VL - 4 UR - http://www.ijdc.net/index.php/ijdc/article/view/134 IS - 3 ER - TY - CONF T1 - An Architecture for an Integrated Fire Emergency Response System for the Built Environment T2 - 9th Symposium of the International Association for Fire Safety Science (IAFSS) Y1 - 2008 A1 - Rochan Upadhyay A1 - Galvin Pringle A1 - George Beckett A1 - Stephen Potter A1 - Liangxiu Han A1 - Stephen Welch A1 - Asif Usmani A1 - Jose Torero KW - emergency response system KW - FireGrid KW - system architecture KW - technology integration AB - FireGrid is a modern concept that aims to leverage a number of modern technologies to aid fire emergency response. In this paper we provide a brief introduction to the FireGrid project. A number of different technologies such as wireless sensor networks, grid-enabled High Performance Computing (HPC) implementation of fire models, and artificial intelligence tools need to be integrated to build up a modern fire emergency response system. We propose a system architecture that provides the framework for integration of the various technologies. We describe the components of the generic FireGrid system architecture in detail. Finally we present a small-scale demonstration experiment which has been completed to highlight the concept and application of the FireGrid system to an actual fire. Although our proposed system architecture provides a versatile framework for integration, a number of new and interesting research problems need to be solved before actual deployment of the system. We outline some of the challenges involved which require significant interdisciplinary collaborations. JF - 9th Symposium of the International Association for Fire Safety Science (IAFSS) PB - IAFSS CY - Karlsruhe, GERMANY ER - TY - CHAP T1 - Contraction-Based Heuristics to Improve the Efficiency of Algorithms Solving the Graph Colouring Problem T2 - Studies in Computational Intelligence Y1 - 2008 A1 - Juhos, I. A1 - van Hemert, J. I. ED - Cotta, C. ED - van Hemert, J. I. KW - constraint satisfaction KW - evolutionary computation KW - graph colouring JF - Studies in Computational Intelligence PB - Springer ER - TY - JOUR T1 - Distributed Computing Education, Part 1: A Special Case? JF - IEEE Distributed Systems Online Y1 - 2008 A1 - Fergusson, D. A1 - Hopkins, R. A1 - Romano, D. A1 - Vander Meer, E. A1 - Atkinson, M. VL - 9 UR - http://dsonline.computer.org/portal/site/dsonline/menuitem.9ed3d9924aeb0dcd82ccc6716bbe36ec/index.jsp?&pName=dso_level1&path=dsonline/2008/06&file=o6002edu.xml&xsl=article.xsl&;jsessionid=LZ5zjySvc2xPnVv4qTYJXhlvwSnRGGj7S7WvPtrPyv23rJGQdjJr!982319602 IS - 6 ER - TY - JOUR T1 - Distributed Computing Education, Part 2: International Summer Schools JF - IEEE Distributed Systems Online Y1 - 2008 A1 - Fergusson, D. A1 - Hopkins, R. A1 - Romano, D. A1 - Vander Meer, E. A1 - Atkinson, M. VL - 9 UR - http://dsonline.computer.org/portal/site/dsonline/menuitem.9ed3d9924aeb0dcd82ccc6716bbe36ec/index.jsp?&pName=dso_level1&path=dsonline/2008/07&file=o7002edu.xml&xsl=article.xsl& IS - 7 ER - TY - CONF T1 - Eliminating the Middle Man: Peer-to-Peer Dataflow T2 - HPDC '08: Proceedings of the 17th International Symposium on High Performance Distributed Computing Y1 - 2008 A1 - Barker, Adam A1 - Weissman, Jon B. A1 - van Hemert, Jano KW - grid computing KW - workflow JF - HPDC '08: Proceedings of the 17th International Symposium on High Performance Distributed Computing PB - ACM ER - TY - Generic T1 - European Graduate Student Workshop on Evolutionary Computation Y1 - 2008 A1 - Di Chio, Cecilia A1 - Giacobini, Mario A1 - van Hemert, Jano ED - Di Chio, Cecilia ED - Giacobini, Mario ED - van Hemert, Jano KW - evolutionary computation AB - Evolutionary computation involves the study of problem-solving and optimization techniques inspired by principles of evolution and genetics. As any other scientific field, its success relies on the continuity provided by new researchers joining the field to help it progress. One of the most important sources for new researchers is the next generation of PhD students that are actively studying a topic relevant to this field. It is from this main observation the idea arose of providing a platform exclusively for PhD students. ER - TY - Generic T1 - Evolutionary Computation in Combinatorial Optimization, 8th European Conference T2 - Lecture Notes in Computer Science Y1 - 2008 A1 - van Hemert, Jano A1 - Cotta, Carlos ED - van Hemert, Jano ED - Cotta, Carlos KW - evolutionary computation AB - Metaheuristics have shown to be effective for difficult combinatorial optimization problems appearing in various industrial, economical, and scientific domains. Prominent examples of metaheuristics are evolutionary algorithms, tabu search, simulated annealing, scatter search, memetic algorithms, variable neighborhood search, iterated local search, greedy randomized adaptive search procedures, ant colony optimization and estimation of distribution algorithms. Problems solved successfully include scheduling, timetabling, network design, transportation and distribution, vehicle routing, the travelling salesman problem, packing and cutting, satisfiability and general mixed integer programming. EvoCOP began in 2001 and has been held annually since then. It is the first event specifically dedicated to the application of evolutionary computation and related methods to combinatorial optimization problems. Originally held as a workshop, EvoCOP became a conference in 2004. The events gave researchers an excellent opportunity to present their latest research and to discuss current developments and applications. Following the general trend of hybrid metaheuristics and diminishing boundaries between the different classes of metaheuristics, EvoCOP has broadened its scope over the last years and invited submissions on any kind of metaheuristic for combinatorial optimization. JF - Lecture Notes in Computer Science PB - Springer VL - LNCS 4972 ER - TY - CONF T1 - Fostering e-Infrastructures: from user-designer relations to community engagement T2 - Symposium on Project Management in e-Science Y1 - 2008 A1 - Voss, A. A1 - Asgari-Targhi, M. A1 - Halfpenny, P. A1 - Procter, R. A1 - Anderson, S. A1 - Dunn, S. A1 - Fragkouli, E. A1 - Hughes, L. A1 - Atkinson, M. A1 - Fergusson, D. A1 - Mineter, M. A1 - Rodden, T. AB - In this paper we discuss how e-Science can draw on the findings, approaches and methods developed in other disciplines to foster e-Infrastructures for research. We also discuss the issue of making user involvement in IT development scale across an open ommunity of researchers and from single systems to distributed e-Infrastructures supporting collaborative research. JF - Symposium on Project Management in e-Science CY - Oxford ER - TY - CONF T1 - Graph Colouring Heuristics Guided by Higher Order Graph Properties T2 - Lecture Notes in Computer Science Y1 - 2008 A1 - Juhos, Istv\'{a}n A1 - van Hemert, Jano ED - van Hemert, Jano ED - Cotta, Carlos KW - evolutionary computation KW - graph colouring AB - Graph vertex colouring can be defined in such a way where colour assignments are substituted by vertex contractions. We present various hyper-graph representations for the graph colouring problem all based on the approach where vertices are merged into groups. In this paper, we show this provides a uniform and compact way to define algorithms, both of a complete or a heuristic nature. Moreover, the representation provides information useful to guide algorithms during their search. In this paper we focus on the quality of solutions obtained by graph colouring heuristics that make use of higher order properties derived during the search. An evolutionary algorithm is used to search permutations of possible merge orderings. JF - Lecture Notes in Computer Science PB - Springer VL - 4972 ER - TY - JOUR T1 - A Grid infrastructure for parallel and interactive applications JF - Computing and Informatics Y1 - 2008 A1 - Gomes, J. A1 - Borges, B. A1 - Montecelo, M. A1 - David, M. A1 - Silva, B. A1 - Dias, N. A1 - Martins, JP A1 - Fernandez, C. A1 - Garcia-Tarres, L. , A1 - Veiga, C. A1 - Cordero, D. A1 - Lopez, J. A1 - J Marco A1 - Campos, I. A1 - Rodríguez, David A1 - Marco, R. A1 - Lopez, A. A1 - Orviz, P. A1 - Hammad, A. VL - 27 IS - 2 ER - TY - CONF T1 - Matching Spatial Regions with Combinations of Interacting Gene Expression Patterns T2 - Communications in Computer and Information Science Y1 - 2008 A1 - van Hemert, J. I. A1 - Baldock, R. A. ED - M. Elloumi ED - \emph ED - et al KW - biomedical KW - data mining KW - DGEMap KW - e-Science AB - The Edinburgh Mouse Atlas aims to capture in-situ gene expression patterns in a common spatial framework. In this study, we construct a grammar to define spatial regions by combinations of these patterns. Combinations are formed by applying operators to curated gene expression patterns from the atlas, thereby resembling gene interactions in a spatial context. The space of combinations is searched using an evolutionary algorithm with the objective of finding the best match to a given target pattern. We evaluate the method by testing its robustness and the statistical significance of the results it finds. JF - Communications in Computer and Information Science PB - Springer Verlag ER - TY - CONF T1 - A novel visual discriminator on network traffic pattern T2 - The Second International Conference on Advanced Engineering Computing and Applications in Sciences (ADVCOMP 2008) Y1 - 2008 A1 - Liangxiu Han A1 - J. Hemert AB - The wavelet transform has been shown to be a powerful tool for characterising network traffic. However, the resulting decomposition of a wavelet transform typically forms a high-dimension space. This is obviously problematic on compact representations, visualizations, and modelling approaches that are based on these high-dimensional data. In this study, we show how data projection techniques can represent the high-dimensional wavelet decomposition in a low dimensional space to facilitate visual analysis. A low-dimensional representation can significantly reduce the model complexity. Hence, features in the data can be presented with a small number of parameters. We demonstrate these projections in the context of network traffic pattern analysis. The experimental results show that the proposed method can effectively discriminate between different application flows, such as FTP and P2P. JF - The Second International Conference on Advanced Engineering Computing and Applications in Sciences (ADVCOMP 2008) PB - IEEE Computer Society CY - Valencia, Spain ER - TY - CONF T1 - OGSA-DAI: Middleware for Data Integration: Selected Applications T2 - ESCIENCE '08: Proceedings of the 2008 Fourth IEEE International Conference on eScience Y1 - 2008 A1 - Grant, Alistair A1 - Antonioletti, Mario A1 - Hume, Alastair C. A1 - Krause, Amy A1 - Dobrzelecki, Bartosz A1 - Jackson, Michael J. A1 - Parsons, Mark A1 - Atkinson, Malcolm P. A1 - Theocharopoulos, Elias JF - ESCIENCE '08: Proceedings of the 2008 Fourth IEEE International Conference on eScience PB - IEEE Computer Society CY - Washington, DC, USA SN - 978-0-7695-3535-7 ER - TY - CONF T1 - Orchestrating Data-Centric Workflows T2 - The 8th IEEE International Symposium on Cluster Computing and the Grid (CCGrid) Y1 - 2008 A1 - Barker, Adam A1 - Weissman, Jon B. A1 - van Hemert, Jano KW - grid computing KW - workflow JF - The 8th IEEE International Symposium on Cluster Computing and the Grid (CCGrid) PB - IEEE Computer Society ER - TY - BOOK T1 - Recent Advances in Evolutionary Computation for Combinatorial Optimization T2 - Studies in Computational Intelligence Y1 - 2008 A1 - Cotta, Carlos A1 - van Hemert, Jano AB - Combinatorial optimisation is a ubiquitous discipline whose usefulness spans vast applications domains. The intrinsic complexity of most combinatorial optimisation problems makes classical methods unaffordable in many cases. To acquire practical solutions to these problems requires the use of metaheuristic approaches that trade completeness for pragmatic effectiveness. Such approaches are able to provide optimal or quasi-optimal solutions to a plethora of difficult combinatorial optimisation problems. The application of metaheuristics to combinatorial optimisation is an active field in which new theoretical developments, new algorithmic models, and new application areas are continuously emerging. This volume presents recent advances in the area of metaheuristic combinatorial optimisation, with a special focus on evolutionary computation methods. Moreover, it addresses local search methods and hybrid approaches. In this sense, the book includes cutting-edge theoretical, methodological, algorithmic and applied developments in the field, from respected experts and with a sound perspective. JF - Studies in Computational Intelligence PB - Springer VL - 153 SN - 978-3-540-70806-3 UR - http://www.springer.com/engineering/book/978-3-540-70806-3 ER - TY - CONF T1 - Scientific Workflow: A Survey and Research Directions T2 - Lecture Notes in Computer Science Y1 - 2008 A1 - Barker, Adam A1 - van Hemert, Jano KW - e-Science KW - workflow AB - Workflow technologies are emerging as the dominant approach to coordinate groups of distributed services. However with a space filled with competing specifications, standards and frameworks from multiple domains, choosing the right tool for the job is not always a straightforward task. Researchers are often unaware of the range of technology that already exists and focus on implementing yet another proprietary workflow system. As an antidote to this common problem, this paper presents a concise survey of existing workflow technology from the business and scientific domain and makes a number of key suggestions towards the future development of scientific workflow systems. JF - Lecture Notes in Computer Science PB - Springer VL - 4967 UR - http://dx.doi.org/10.1007/978-3-540-68111-3_78 ER - TY - JOUR T1 - The Self-adaptation to dynamic failures for efficient Virtual Organization formation in Grid computing context JF - Chaos, Solitons and Fractals Y1 - 2008 A1 - Liangxiu Han KW - complex network system KW - failure recovery KW - graph theory KW - grid computing KW - virtual organization formation AB - Grid computing aims to enable “resource sharing and coordinated problem solving in dynamic, multi-institutional Virtual Organizations (VOs)”. However, due to the nature of heterogeneous and dynamic resources, dynamic failures in the distributed grid environment usually occur more than in traditional computation platforms, which cause failed VO formations. In this paper, we develop a novel self-adaptive mechanism to dynamic failures during VO formations. Such a self-adaptive scheme allows an individual and member of VOs to automatically find other available or replaceable one once a failure happens and therefore makes systems automatically recover from dynamic failures. We define dynamic failure situations of a system by using two standard indicators: Mean Time between Failures (MTBF) and Mean Time to Recover (MTTR). We model both MTBF and MTTR as Poisson distributions. We investigate and analyze the efficiency of the proposed self-adaptation mechanism to dynamic failures by comparing the success probability of VO formations before and after adopting it in three different cases: 1) different failure situations; 2) different organizational structures and scales; 3) different task complexities. The experimental results show that the proposed scheme can automatically adapt to dynamic failures and effectively improve the dynamic VO formation performance in the event of node failures, which provide a valuable addition to the field. PB - Elsevier Science ER - TY - JOUR T1 - Semantic-Supported and Agent-Based Decentralized Grid Resource Discovery JF - Future Generation Computer Systems Y1 - 2008 A1 - Liangxiu Han A1 - Dave Berry KW - grid resource discovery, decentralization, agent, semantic similarity, ontology AB - One of open issues in grid computing is efficient resource discovery. In this paper, we propose a novel semantic-supported and agent-based decentralized grid resource discovery mechanism. Without overhead of negotiation, the algorithm allows individual resource agents to semantically interact with neighbour agents based on local knowledge and dynamically form a resource service chain to complete a task. The algorithm ensures resource agent’s ability to cooperate and coordinate on neighbour knowledge requisition for flexible problem solving. The developed algorithm is evaluated by investigating the relationship between the success probability of resource discovery and semantic similarity under different factors. The experiments show the algorithm could flexibly and dynamically discover resources and therefore provide a valuable addition to the field. PB - ScienceDirect VL - 24 IS - 8 ER - TY - CONF T1 - Widening Uptake of e-Infrastructure Services T2 - 4th International Conference on e-Social Science Y1 - 2008 A1 - Voss, A. A1 - Asgari-Targhi, M. A1 - Procter, R. A1 - Halfpenny, P. A1 - Dunn, S. A1 - Fragkouli, E. A1 - Anderson, S. A1 - Hughes, L. A1 - Mineter, M. A1 - Fergusson, D. A1 - Atkinson, M. AB - This paper presents findings from the e-Uptake project which aims to widen the uptake of e-Infrastructure Services for research. We focus specifically on the identification of barriers and enablers of uptake and the taxonomy developed to structure our findings. Based on these findings, we describe the development of a number of interventions such as training and outreach events, workshops and the deployment of a UK 'one-stop-shop' for support and event information as well as training material. Finally, we will describe how the project relates to other ongoing community engagement efforts in the UK and worldwide. Introduction Existing investments in e-Science and Grid computing technologies have helped to develop the capacity to build e-Infrastructures for research: distributed, networked, interoperable computing and data resources that are available to underpin a wide range of research activities in all research disciplines. In the UK, the Research Councils and the JISC are funding programmes to support the development of essential components of such infrastructures such as National Grid Service (www.ngs.ac.uk) or the UK Access Management Federation (www.ukfederation.org.uk) as well as discipline-specific efforts to build consistent and accessible instantiations of e-Infrastructures, for example the e- Infrastructure for the Social Sciences (Daw et al. 2007). These investments are complemented by an active programme of community engagement (Voss et al. 2007). As part of the community engagement strand of its e-Infrastructure programme, JISC has funded the e-Uptake project, a collaboration between the ESRC National Centre for e-Social Science at the University of Manchester, the Arts & Humanities e-Science Support Centre at King's College London and the National e-Science Centre at the University of Edinburgh. In this paper we present the project's activities to date to widen the uptake of e-Infrastructure services by eliciting information about the barriers to and enablers of uptake, developing adequate interventions such as training and outreach events, running workshops and the deploying a UK 'one-stop-shop' for support and event information as well as training material. JF - 4th International Conference on e-Social Science CY - Manchester UR - http://www.ncess.ac.uk/events/conference/programme/workshop1/?ref=/programme/thurs/1aVoss.htm ER - TY - CONF T1 - WikiSim: simulating knowledge collection and curation in structured wikis. T2 - Proceedings of the 2008 International Symposium on Wikis in Porto, Portugal Y1 - 2008 A1 - De~Ferrari, Luna A1 - Stuart Aitken A1 - van Hemert, Jano A1 - Goryanin, Igor AB - The aim of this work is to model quantitatively one of the main properties of wikis: how high quality knowledge can emerge from the individual work of independent volunteers. The approach chosen is to simulate knowledge collection and curation in wikis. The basic model represents the wiki as a set of of true/false values, added and edited at each simulation round by software agents (users) following a fixed set of rules. The resulting WikiSim simulations already manage to reach distributions of edits and user contributions very close to those reported for Wikipedia. WikiSim can also span conditions not easily measurable in real-life wikis, such as the impact of various amounts of user mistakes. WikiSim could be extended to model wiki software features, such as discussion pages and watch lists, while monitoring the impact they have on user actions and consensus, and their effect on knowledge quality. The method could also be used to compare wikis with other curation scenarios based on centralised editing by experts. The future challenges for WikiSim will be to find appropriate ways to evaluate and validate the models and to keep them simple while still capturing relevant properties of wiki systems. JF - Proceedings of the 2008 International Symposium on Wikis in Porto, Portugal PB - ACM CY - New York, NY, USA ER - TY - CONF T1 - Data Integration in eHealth: A Domain/Disease Specific Roadmap T2 - Studies in Health Technology and Informatics Y1 - 2007 A1 - Ure, J. A1 - Proctor, R. A1 - Martone, M. A1 - Porteous, D. A1 - Lloyd, S. A1 - Lawrie, S. A1 - Job, D. A1 - Baldock, R. A1 - Philp, A. A1 - Liewald, D. A1 - Rakebrand, F. A1 - Blaikie, A. A1 - McKay, C. A1 - Anderson, S. A1 - Ainsworth, J. A1 - van Hemert, J. A1 - Blanquer, I. A1 - Sinno ED - N. Jacq ED - Y. Legr{\'e} ED - H. Muller ED - I. Blanquer ED - V. Breton ED - D. Hausser ED - V. Hern{\'a}ndez ED - T. Solomonides ED - M. Hofman-Apitius KW - e-Science AB - The paper documents a series of data integration workshops held in 2006 at the UK National e-Science Centre, summarizing a range of the problem/solution scenarios in multi-site and multi-scale data integration with six HealthGrid projects using schizophrenia as a domain-specific test case. It outlines emerging strategies, recommendations and objectives for collaboration on shared ontology-building and harmonization of data for multi-site trials in this domain. JF - Studies in Health Technology and Informatics PB - IOPress VL - 126 SN - 978-1-58603-738-3 ER - TY - CONF T1 - e-Research Infrastructure Development and Community Engagement T2 - All Hands Meeting 2007 Y1 - 2007 A1 - Voss, A. A1 - Mascord, M. A1 - Fraser, M. A1 - Jirotka, M. A1 - Procter, R. A1 - Halfpenny, P. A1 - Fergusson, D. A1 - Atkinson, M. A1 - Dunn, S. A1 - Blanke, T. A1 - Hughes, L. A1 - Anderson, S. AB - The UK and wider international e-Research initiatives are entering a critical phase in which they need to move from the development of the basic underlying technology, demonstrators, prototypes and early applications to wider adoption and the development of stable infrastructures. In this paper we will review existing work on studies of infrastructure and community development, requirements elicitation for existing services as well as work within the arts and humanities and the social sciences to establish e-Research in these communities. We then describe two projects recently funded by JISC to study barriers to adoption and responses to them as well as use cases and service usage models. JF - All Hands Meeting 2007 CY - Nottingham, UK ER - TY - Generic T1 - European Graduate Student Workshop on Evolutionary Computation Y1 - 2007 A1 - Giacobini, Mario A1 - van Hemert, Jano ED - Mario Giacobini ED - van Hemert, Jano KW - evolutionary computation AB - Evolutionary computation involves the study of problem-solving and optimization techniques inspired by principles of evolution and genetics. As any other scientific field, its success relies on the continuity provided by new researchers joining the field to help it progress. One of the most important sources for new researchers is the next generation of PhD students that are actively studying a topic relevant to this field. It is from this main observation the idea arose of providing a platform exclusively for PhD students. CY - Valencia, Spain ER - TY - Generic T1 - Evolutionary Computation in Combinatorial Optimization, 7th European Conference T2 - Lecture Notes in Computer Science Y1 - 2007 A1 - Cotta, Carlos A1 - van Hemert, Jano ED - Carlos Cotta ED - van Hemert, Jano KW - evolutionary computation AB - Metaheuristics have often been shown to be effective for difficult combinatorial optimization problems appearing in various industrial, economical, and scientific domains. Prominent examples of metaheuristics are evolutionary algorithms, simulated annealing, tabu search, scatter search, memetic algorithms, variable neighborhood search, iterated local search, greedy randomized adaptive search procedures, estimation of distribution algorithms, and ant colony optimization. Successfully solved problems include scheduling, timetabling, network design, transportation and distribution, vehicle routing, the traveling salesman problem, satisfiability, packing and cutting, and general mixed integer programming. EvoCOP began in 2001 and has been held annually since then. It was the first event specifically dedicated to the application of evolutionary computation and related methods to combinatorial optimization problems. Originally held as a workshop, EvoCOP became a conference in 2004. The events gave researchers an excellent opportunity to present their latest research and to discuss current developments and applications as well as providing for improved interaction between members of this scientific community. Following the general trend of hybrid metaheuristics and diminishing boundaries between the different classes of metaheuristics, EvoCOP has broadened its scope over the last years and invited submissions on any kind of metaheuristic for combinatorial optimization. JF - Lecture Notes in Computer Science PB - Springer VL - LNCS 4446 UR - http://springerlink.metapress.com/content/105633/ ER - TY - CONF T1 - Grid Enabling Your Data Resources with OGSA-DAI T2 - Applied Parallel Computing. State of the Art in Scientific Computing Y1 - 2007 A1 - Antonioletti, M. A1 - Atkinson, M. A1 - Chue Hong, N. P. A1 - Dobrzelecki, B. A1 - Hume, A. C. A1 - Jackson, M. A1 - Karasavvas, K. A1 - Krause, A. A1 - Schopf, J. M. A1 - Sugden. T. A1 - Theocharopoulos, E. JF - Applied Parallel Computing. State of the Art in Scientific Computing T3 - Lecture Notes in Computer Science VL - 4699 ER - TY - CONF T1 - Interaction as a Grounding for Peer to Peer Knowledge Sharing T2 - Advances in Web Semantics Y1 - 2007 A1 - Robertson, D. A1 - Walton, C. A1 - Barker, A. A1 - Besana, P. A1 - Chen-Burger, Y. A1 - Hassan, F. A1 - Lambert, D. A1 - Li, G. A1 - McGinnis, J A1 - Osman, N. A1 - Bundy, A. A1 - McNeill, F. A1 - van Harmelen, F. A1 - Sierra, C. A1 - Giunchiglia, F. JF - Advances in Web Semantics PB - LNCS-IFIP VL - 1 ER - TY - JOUR T1 - MAPFS-DAI, an extension of OGSA-DAI based on a parallel file system JF - Future Generation Computer Systems Y1 - 2007 A1 - Sanchez, A. A1 - Perez, M. S. A1 - Karasavvas, K. A1 - Herrero, P. A1 - Perez, A. VL - 23 ER - TY - CONF T1 - Mining spatial gene expression data for association rules T2 - Lecture Notes in Bioinformatics Y1 - 2007 A1 - van Hemert, J. I. A1 - Baldock, R. A. ED - S. Hochreiter ED - R. Wagner KW - biomedical KW - data mining KW - DGEMap KW - e-Science AB - We analyse data from the Edinburgh Mouse Atlas Gene-Expression Database (EMAGE) which is a high quality data source for spatio-temporal gene expression patterns. Using a novel process whereby generated patterns are used to probe spatially-mapped gene expression domains, we are able to get unbiased results as opposed to using annotations based predefined anatomy regions. We describe two processes to form association rules based on spatial configurations, one that associates spatial regions, the other associates genes. JF - Lecture Notes in Bioinformatics PB - Springer Verlag UR - http://dx.doi.org/10.1007/978-3-540-71233-6_6 ER - TY - CONF T1 - OGSA-DAI 3.0 - The What's and Whys T2 - UK e-Science All Hands Meeting Y1 - 2007 A1 - Antonioletti, M. A1 - Hong, N. P. Chue A1 - Hume, A. C. A1 - Jackson, M. A1 - Karasavvas, K. A1 - Krause, A. A1 - Schopf, J. M. A1 - Atkinson, M. P. A1 - Dobrzelecki, B. A1 - Illingworth, M. A1 - McDonnell, N. A1 - Parsons, M. A1 - Theocharopoulous, E. JF - UK e-Science All Hands Meeting ER - TY - CONF T1 - Towards a Grid-Enabled Simulation Framework for Nano-CMOS Electronics T2 - 3rd IEEE International Conference on eScience and Grid Computing Y1 - 2007 A1 - Liangxiu Han A1 - Asen Asenov A1 - Dave Berry A1 - Campbell Millar A1 - Gareth Roy A1 - Scott Roy A1 - Richard Sinnott A1 - Gordon Stewart AB - The electronics design industry is facing major challenges as transistors continue to decrease in size. The next generation of devices will be so small that the position of individual atoms will affect their behaviour. This will cause the transistors on a chip to have highly variable characteristics, which in turn will impact circuit and system design tools. The EPSRC project “Meeting the Design Challenges of Nano-CMOS Electronics” (Nano-CMOS) has been funded to explore this area. In this paper, we describe the distributed data-management and computing framework under development within Nano-CMOS. A key aspect of this framework is the need for robust and reliable security mechanisms that support distributed electronics design groups who wish to collaborate by sharing designs, simulations, workflows, datasets and computation resources. This paper presents the system design, and an early prototype of the project which hasbeen useful in helping us to understand the benefits of such a grid infrastructure. In particular, we also present two typical use cases: user authentication, and execution of large-scale device simulations. JF - 3rd IEEE International Conference on eScience and Grid Computing PB - IEEE Computer Society CY - Bangalore, India ER - TY - CONF T1 - EGEE: building a pan-European grid training organisation T2 - ACSW Frontiers Y1 - 2006 A1 - Berlich, R{\"u}diger A1 - Hardt, Marcus A1 - Kunze, Marcel A1 - Atkinson, Malcolm P. A1 - Fergusson, David JF - ACSW Frontiers ER - TY - Generic T1 - European Graduate Student Workshop on Evolutionary Computation Y1 - 2006 A1 - Giacobini, Mario A1 - van Hemert, Jano ED - Giacobini, Mario ED - van Hemert, Jano KW - evolutionary computation AB - Evolutionary computation involves the study of problem-solving and optimization techniques inspired by principles of evolution and genetics. As any other scientific field, its success relies on the continuity provided by new researchers joining the field to help it progress. One of the most important sources for new researchers is the next generation of PhD students that are actively studying a topic relevant to this field. It is from this main observation the idea arose of providing a platform exclusively for PhD students. CY - Budapest, Hungary ER - TY - JOUR T1 - Evolving combinatorial problem instances that are difficult to solve JF - Evolutionary Computation Y1 - 2006 A1 - van Hemert, J. I. KW - constraint programming KW - constraint satisfaction KW - evolutionary computation KW - problem evolving KW - satisfiability KW - travelling salesman AB - In this paper we demonstrate how evolutionary computation can be used to acquire difficult to solve combinatorial problem instances, thereby stress-testing the corresponding algorithms used to solve these instances. The technique is applied in three important domains of combinatorial optimisation, binary constraint satisfaction, Boolean satisfiability, and the travelling salesman problem. Problem instances acquired through this technique are more difficult than ones found in popular benchmarks. We analyse these evolved instances with the aim to explain their difficulty in terms of structural properties, thereby exposing the weaknesses of corresponding algorithms. VL - 14 UR - http://www.mitpressjournals.org/toc/evco/14/4 ER - TY - CONF T1 - Grid Enabling your Data Resources with OGSA-DAI T2 - Workshop on State-of-the-Art in Scientific and Parallel Computing Y1 - 2006 A1 - Antonioletti, M. A1 - Atkinson, M. A1 - Hong, N. Chue A1 - Dobrzelecki, B. A1 - Hume, A. A1 - Jackson, M. A1 - Karasavvas, K. A1 - Krause, A. A1 - Sugden, T. A1 - Theocharopoulos, E. JF - Workshop on State-of-the-Art in Scientific and Parallel Computing ER - TY - CONF T1 - Improving Graph Colouring Algorithms and Heuristics Using a Novel Representation T2 - Springer Lecture Notes on Computer Science Y1 - 2006 A1 - Juhos, I. A1 - van Hemert, J. I. ED - J. Gottlieb ED - G. Raidl KW - constraint satisfaction KW - graph colouring AB - We introduce a novel representation for the graph colouring problem, called the Integer Merge Model, which aims to reduce the time complexity of an algorithm. Moreover, our model provides useful information for guiding heuristics as well as a compact description for algorithms. To verify the potential of the model, we use it in dsatur, in an evolutionary algorithm, and in the same evolutionary algorithm extended with heuristics. An empiricial investigation is performed to show an increase in efficiency on two problem suites , a set of practical problem instances and a set of hard problem instances from the phase transition. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag ER - TY - JOUR T1 - Increasing the efficiency of graph colouring algorithms with a representation based on vector operations JF - Journal of Software Y1 - 2006 A1 - Juhos, I. A1 - van Hemert, J. I. KW - graph colouring AB - We introduce a novel representation for the graph colouring problem, called the Integer Merge Model, which aims to reduce the time complexity of graph colouring algorithms. Moreover, this model provides useful information to aid in the creation of heuristics that can make the colouring process even faster. It also serves as a compact definition for the description of graph colouring algorithms. To verify the potential of the model, we use it in the complete algorithm DSATUR, and in two version of an incomplete approximation algorithm; an evolutionary algorithm and the same evolutionary algorithm extended with guiding heuristics. Both theoretical and empirical results are provided investigation is performed to show an increase in the efficiency of solving graph colouring problems. Two problem suites were used for the empirical evidence: a set of practical problem instances and a set of hard problem instances from the phase transition. VL - 1 ER - TY - CONF T1 - Neighborhood Searches for the Bounded Diameter Minimum Spanning Tree Problem Embedded in a VNS, EA, and ACO T2 - Proceedings of the Genetic and Evolutionary Computation Conference (GECCO 2006) Y1 - 2006 A1 - Gruber, M. A1 - van Hemert, J. I. A1 - Raidl, G. R. ED - Maarten Keijzer ED - et al KW - constraint satisfaction KW - evolutionary computation KW - variable neighbourhood search AB - We consider the Bounded Diameter Minimum Spanning Tree problem and describe four neighbourhood searches for it. They are used as local improvement strategies within a variable neighbourhood search (VNS), an evolutionary algorithm (EA) utilising a new encoding of solutions, and an ant colony optimisation (ACO).We compare the performance in terms of effectiveness between these three hybrid methods on a suite f popular benchmark instances, which contains instances too large to solve by current exact methods. Our results show that the EA and the ACO outperform the VNS on almost all used benchmark instances. Furthermore, the ACO yields most of the time better solutions than the EA in long-term runs, whereas the EA dominates when the computation time is strongly restricted. JF - Proceedings of the Genetic and Evolutionary Computation Conference (GECCO 2006) PB - ACM CY - Seattle, USA VL - 2 ER - TY - CONF T1 - Profiling OGSA-DAI Performance for Common Use Patterns T2 - UK e-Science All Hands Meeting Y1 - 2006 A1 - Dobrzelecki, B. A1 - Antonioletti, M. A1 - Schopf, J. M. A1 - Hume, A. C. A1 - Atkinson, M. A1 - Hong, N. P. Chue A1 - Jackson, M. A1 - Karasavvas, K. A1 - Krause, A. A1 - Parsons, M. A1 - Sugden, T. A1 - Theocharopoulos, E. JF - UK e-Science All Hands Meeting ER - TY - CONF T1 - Complexity Transitions in Evolutionary Algorithms: Evaluating the impact of the initial population T2 - Proceedings of the Congress on Evolutionary Computation Y1 - 2005 A1 - Defaweux, A. A1 - Lenaerts, T. A1 - van Hemert, J. I. A1 - Parent, J. KW - constraint satisfaction KW - transition models AB - This paper proposes an evolutionary approach for the composition of solutions in an incremental way. The approach is based on the metaphor of transitions in complexity discussed in the context of evolutionary biology. Partially defined solutions interact and evolve into aggregations until a full solution for the problem at hand is found. The impact of the initial population on the outcome and the dynamics of the process is evaluated using the domain of binary constraint satisfaction problems. JF - Proceedings of the Congress on Evolutionary Computation PB - {IEEE} Press ER - TY - CONF T1 - Cross-Layer Peer-to-Peer Traffic Identification and Optimization Based on Active Networking T2 - 7th International Working Conference on Active and Programmable Networks Y1 - 2005 A1 - Dedinski, I. A1 - De Meer, H. A1 - Liangxiu Han A1 - Mathy, L. A1 - Pezaros, D. A1 - P. , Sventek, J. S. A1 - Xiaoying, Z. JF - 7th International Working Conference on Active and Programmable Networks CY - Sophia Antipolis, French Riviera, La Cote d'Azur, France, November 21-23, 2005. ER - TY - JOUR T1 - The design and implementation of Grid database services in OGSA-DAI JF - Concurrency - Practice and Experience Y1 - 2005 A1 - Antonioletti, Mario A1 - Atkinson, Malcolm P. A1 - Baxter, Robert M. A1 - Borley, Andrew A1 - Hong, Neil P. Chue A1 - Collins, Brian A1 - Hardman, Neil A1 - Hume, Alastair C. A1 - Knox, Alan A1 - Mike Jackson A1 - Krause, Amrey A1 - Laws, Simon A1 - Magowan, James A1 - Pato VL - 17 ER - TY - CONF T1 - Evolutionary Transitions as a Metaphor for Evolutionary Optimization T2 - LNAI 3630 Y1 - 2005 A1 - Defaweux, A. A1 - Lenaerts, T. A1 - van Hemert, J. I. ED - M. Capcarrere ED - A. A. Freitas ED - P. J. Bentley ED - C. G. Johnson ED - J. Timmis KW - constraint satisfaction KW - transition models AB - This paper proposes a computational model for solving optimisation problems that mimics the principle of evolutionary transitions in individual complexity. More specifically it incorporates mechanisms for the emergence of increasingly complex individuals from the interaction of more simple ones. The biological principles for transition are outlined and mapped onto an evolutionary computation context. The class of binary constraint satisfaction problems is used to illustrate the transition mechanism. JF - LNAI 3630 PB - Springer-Verlag SN - 3-540-28848-1 ER - TY - Generic T1 - Experience with the international testbed in the crossgrid project T2 - Advances in Grid Computing-EGC 2005 Y1 - 2005 A1 - Gomes, J. A1 - David, M. A1 - Martins, J. A1 - Bernardo, L. A1 - A García A1 - Hardt, M. A1 - Kornmayer, H. A1 - Marco, Jesus A1 - Marco, Rafael A1 - Rodríguez, David A1 - Diaz, Irma A1 - Cano, Daniel A1 - Salt, J. A1 - Gonzalez, S. A1 - J Sánchez A1 - Fassi, F. A1 - Lara, V. A1 - Nyczyk, P. A1 - Lason, P. A1 - Ozieblo, A. A1 - Wolniewicz, P. A1 - Bluj, M. A1 - K Nawrocki A1 - A Padee A1 - W Wislicki ED - Peter M. A. Sloot, Alfons G. Hoekstra, Thierry Priol, Alexander Reinefeld ED - Marian Bubak JF - Advances in Grid Computing-EGC 2005 T3 - LNCS PB - Springer Berlin/Heidelberg CY - Amsterdam VL - 3470 ER - TY - Generic T1 - Genetic Programming, Proceedings of the 8th European Conference T2 - Lecture Notes in Computer Science Y1 - 2005 A1 - Keijzer, M. A1 - Tettamanzi, A. A1 - Collet, P. A1 - van Hemert, J. A1 - Tomassini, M. ED - M. Keijzer ED - A. Tettamanzi ED - P. Collet ED - van Hemert, J. ED - M. Tomassini KW - evolutionary computation JF - Lecture Notes in Computer Science PB - Springer VL - 3447 SN - 3-540-25436-6 UR - http://www.springeronline.com/sgw/cda/frontpage/0,11855,3-40100-22-45347265-0,00.html?changeHeader=true ER - TY - CONF T1 - Heuristic Colour Assignment Strategies for Merge Models in Graph Colouring T2 - Springer Lecture Notes on Computer Science Y1 - 2005 A1 - Juhos, I. A1 - Tóth, A. A1 - van Hemert, J. I. ED - G. Raidl ED - J. Gottlieb KW - constraint satisfaction KW - graph colouring AB - In this paper, we combine a powerful representation for graph colouring problems with different heuristic strategies for colour assignment. Our novel strategies employ heuristics that exploit information about the partial colouring in an aim to improve performance. An evolutionary algorithm is used to drive the search. We compare the different strategies to each other on several very hard benchmarks and on generated problem instances, and show where the novel strategies improve the efficiency. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin ER - TY - CONF T1 - Introduction to OGSA-DAI Services T2 - Scientific Applications of Grid Computing Y1 - 2005 A1 - Karasavvas, K. A1 - Antonioletti, M. A1 - Atkinson, M. A1 - Hong, N. C. A1 - Sugden, T. A1 - Hume, A. A1 - Jackson, M. A1 - Krause, A. A1 - Palansuriya, C. JF - Scientific Applications of Grid Computing VL - 3458 SN - 978-3-540-25810-0 ER - TY - CONF T1 - A New Architecture for OGSA-DAI T2 - UK e-Science All Hands Meeting Y1 - 2005 A1 - Atkinson, M. A1 - Karasavvas, K. A1 - Antonioletti, M. A1 - Baxter, R. A1 - Borley, A. A1 - Hong, N. C. A1 - Hume, A. A1 - Jackson, M. A1 - Krause, A. A1 - Laws, S. A1 - Paton, N. A1 - Schopf, J. A1 - Sugden, T. A1 - Tourlas, K. A1 - Watson, P. JF - UK e-Science All Hands Meeting ER - TY - CONF T1 - OGSA-DAI Status and Benchmarks T2 - All Hands Meeting 2005 Y1 - 2005 A1 - Antonioletti, Mario A1 - Malcolm Atkinson A1 - Rob Baxter A1 - Andrew Borle A1 - Hong, Neil P. Chue A1 - Patrick Dantressangle A1 - Hume, Alastair C. A1 - Mike Jackson A1 - Krause, Amy A1 - Laws, Simon A1 - Parsons, Mark A1 - Paton, Norman W. A1 - Jennifer M. Schopf A1 - Tom Sugden A1 - Watson, Paul AB - This paper presents a status report on some of the highlights that have taken place within the OGSADAI project since the last AHM. A description of Release 6.0 functionality and details of the forthcoming release, due in September 2005, is given. Future directions for this project are discussed. This paper also describes initial results of work being done to systematically benchmark recent OGSADAI releases. The OGSA-DAI software distribution, and more information about the project, is available from the project website at www.ogsadai.org.uk. JF - All Hands Meeting 2005 CY - Nottingham, UK ER - TY - CONF T1 - Organization of the International Testbed of the CrossGrid Project T2 - Cracow Grid Workshop 2005 Y1 - 2005 A1 - Gomes, J. A1 - David, M. A1 - Martins, J. A1 - Bernardo, L. A1 - Garcia, A. A1 - Hardt, M. A1 - Kornmayer, H. A1 - Marco, Rafael A1 - Rodríguez, David A1 - Diaz, Irma A1 - Cano, Daniel A1 - Salt, J. A1 - Gonzalez, S. A1 - Sanchez, J. A1 - Fassi, F. A1 - Lara, V. A1 - Nyczyk, P. A1 - Lason, P. A1 - Ozieblo, A. A1 - Wolniewicz, P. A1 - Bluj, M. JF - Cracow Grid Workshop 2005 ER - TY - CONF T1 - Property analysis of symmetric travelling salesman problem instances acquired through evolution T2 - Springer Lecture Notes on Computer Science Y1 - 2005 A1 - van Hemert, J. I. ED - G. Raidl ED - J. Gottlieb KW - problem evolving KW - travelling salesman AB - We show how an evolutionary algorithm can successfully be used to evolve a set of difficult to solve symmetric travelling salesman problem instances for two variants of the Lin-Kernighan algorithm. Then we analyse the instances in those sets to guide us towards deferring general knowledge about the efficiency of the two variants in relation to structural properties of the symmetric travelling salesman problem. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin ER - TY - CONF T1 - Transition Models as an incremental approach for problem solving in Evolutionary Algorithms T2 - Proceedings of the Genetic and Evolutionary Computation Conference Y1 - 2005 A1 - Defaweux, A. A1 - Lenaerts, T. A1 - van Hemert, J. I. A1 - Parent, J. ED - H.-G. Beyer ED - et al KW - constraint satisfaction KW - transition models AB - This paper proposes an incremental approach for building solutions using evolutionary computation. It presents a simple evolutionary model called a Transition model. It lets building units of a solution interact and then uses an evolutionary process to merge these units toward a full solution for the problem at hand. The paper provides a preliminary study on the evolutionary dynamics of this model as well as an empirical comparison with other evolutionary techniques on binary constraint satisfaction. JF - Proceedings of the Genetic and Evolutionary Computation Conference PB - {ACM} Press ER - TY - JOUR T1 - Web Service Grids: an evolutionary approach JF - Concurrency - Practice and Experience Y1 - 2005 A1 - Atkinson, Malcolm P. A1 - Roure, David De A1 - Dunlop, Alistair N. A1 - Fox, Geoffrey A1 - Henderson, Peter A1 - Hey, Anthony J. G. A1 - Paton, Norman W. A1 - Newhouse, Steven A1 - Parastatidis, Savas A1 - Trefethen, Anne E. A1 - Watson, Paul A1 - Webber, Jim VL - 17 ER - TY - CONF T1 - Binary Merge Model Representation of the Graph Colouring Problem T2 - Springer Lecture Notes on Computer Science Y1 - 2004 A1 - Juhos, I. A1 - Tóth, A. A1 - van Hemert, J. I. ED - J. Gottlieb ED - G. Raidl KW - constraint satisfaction KW - graph colouring AB - This paper describes a novel representation and ordering model that aided by an evolutionary algorithm, is used in solving the graph \emph{k}-colouring problem. Its strength lies in reducing the search space by breaking symmetry. An empirical comparison is made with two other algorithms on a standard suit of problem instances and on a suit of instances in the phase transition where it shows promising results. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin SN - 3-540-21367-8 ER - TY - Generic T1 - Development of a Grid Infrastructure for Functional Genomics T2 - Life Science Grid Conference (LSGrid 2004) Y1 - 2004 A1 - Sinnott, R. O. A1 - Bayer, M. A1 - Houghton, D. A1 - D. Berry A1 - Ferrier, M. JF - Life Science Grid Conference (LSGrid 2004) T3 - LNCS PB - Springer Verlag CY - Kanazawa, Japan ER - TY - CONF T1 - Dynamic Routing Problems with Fruitful Regions: Models and Evolutionary Computation T2 - LNCS Y1 - 2004 A1 - van Hemert, J. I. A1 - la Poutré, J. A. ED - Xin Yao ED - Edmund Burke ED - Jose A. Lozano ED - Jim Smith ED - Juan J. Merelo-Guerv\'os ED - John A. Bullinaria ED - Jonathan Rowe ED - Peter Ti\v{n}o Ata Kab\'an ED - Hans-Paul Schwefel KW - dynamic problems KW - evolutionary computation KW - vehicle routing AB - We introduce the concept of fruitful regions in a dynamic routing context: regions that have a high potential of generating loads to be transported. The objective is to maximise the number of loads transported, while keeping to capacity and time constraints. Loads arrive while the problem is being solved, which makes it a real-time routing problem. The solver is a self-adaptive evolutionary algorithm that ensures feasible solutions at all times. We investigate under what conditions the exploration of fruitful regions improves the effectiveness of the evolutionary algorithm. JF - LNCS PB - Springer-Verlag CY - Birmingham, UK VL - 3242 SN - 3-540-23092-0 ER - TY - Generic T1 - Grid Services Supporting the Usage of Secure Federated, Distributed Biomedical Data T2 - All Hands Meeting 2004 Y1 - 2004 A1 - Richard Sinnott A1 - Malcolm Atkinson A1 - Micha Bayer A1 - Dave Berry A1 - Anna Dominiczak A1 - Magnus Ferrier A1 - David Gilbert A1 - Neil Hanlon A1 - Derek Houghton A1 - Hunt, Ela A1 - David White AB - The BRIDGES project is a UK e-Science project that provides grid based support for biomedical research into the genetics of hypertension – the Cardiovascular Functional Genomics Project (CFG). Its main goal is to provide an effective environment for CFG, and biomedical research in general, including access to integrated data, analysis and visualization, with appropriate authorisation and privacy, as well as grid based computational tools and resources. It also aims to provide an improved understanding of the requirements of academic biomedical research virtual organizations and to evaluate the utility of existing data federation tools. JF - All Hands Meeting 2004 CY - Nottingham, UK UR - http://www.allhands.org.uk/2004/proceedings/papers/87.pdf ER - TY - CONF T1 - Grid-Based Metadata Services T2 - SSDBM Y1 - 2004 A1 - Deelman, Ewa A1 - Singh, Gurmeet Singh A1 - Atkinson, Malcolm P. A1 - Chervenak, Ann L. A1 - Hong, Neil P. Chue A1 - Kesselman, Carl A1 - Patil, Sonal A1 - Pearlman, Laura A1 - Su, Mei-Hui JF - SSDBM ER - TY - CONF T1 - OGSA-DAI Status Report and Future Directions T2 - All Hands Meeting 2004 Y1 - 2004 A1 - Antonioletti, Mario A1 - Malcolm Atkinson A1 - Rob Baxter A1 - Borley, Andrew A1 - Hong, Neil P. Chue A1 - Collins, Brian A1 - Jonathan Davies A1 - Desmond Fitzgerald A1 - Hardman, Neil A1 - Hume, Alastair C. A1 - Mike Jackson A1 - Krause, Amrey A1 - Laws, Simon A1 - Paton, Norman W. A1 - Tom Sugden A1 - Watson, Paul A1 - Mar AB - Data Access and Integration (DAI) of data resources, such as relational and XML databases, within a Grid context. Project members also participate in the development of DAI standards through the GGF DAIS WG. The standards that emerge through this effort will be adopted by OGSA-DAI once they have stabilised. The OGSA-DAI developers are also engaging with a growing user community to gather their data and functionality requirements. Several large projects are already using OGSA-DAI to provide their DAI capabilities. This paper presents a status report on OGSA-DAI activities since the last AHM and announces future directions. The OGSA-DAI software distribution and more information about the project is available from the project website at http://www.ogsadai.org.uk/. JF - All Hands Meeting 2004 CY - Nottingham, UK ER - TY - CONF T1 - OGSA-DAI: Two Years On T2 - GGF10 Y1 - 2004 A1 - Antonioletti, Mario A1 - Malcolm Atkinson A1 - Rob Baxter A1 - Borley, Andrew A1 - Neil Chue Hong A1 - Collins, Brian A1 - Jonathan Davies A1 - Hardman, Neil A1 - George Hicken A1 - Ally Hume A1 - Mike Jackson A1 - Krause, Amrey A1 - Laws, Simon A1 - Magowan, James A1 - Jeremy Nowell A1 - Paton, Norman W. A1 - Dave Pearson A1 - To AB - The OGSA-DAI project has been producing Grid-enabled middleware for almost two years now, providing data access and integration capabilities to data resources, such as databases, within an OGSA context. In these two years, OGSA-DAI has been tracking rapidly evolving standards, managing changes in software dependencies, contributing to the standardisation process and liasing with a growing user community together with their associated data requirements. This process has imparted important lessons and raised a number of issues that need to be addressed if a middleware product is to be widely adopted. This paper examines the experiences of OGSA-DAI in implementing proposed standards, the likely impact that the still-evolving standards landscape will have on future implementations and how these affect uptake of the software. The paper also examines the gathering of requirements from and engagement with the Grid community, the difficulties of defining a process for the management and publishing of metadata, and whether relevant standards can be implemented in an efficient manner. The OGSA-DAI software distribution and more details about the project are available from the project Web site at http://www.ogsadai.org.uk/. JF - GGF10 CY - Berlin, Germany ER - TY - CONF T1 - Phase transition properties of clustered travelling salesman problem instances generated with evolutionary computation T2 - LNCS Y1 - 2004 A1 - van Hemert, J. I. A1 - Urquhart, N. B. ED - Xin Yao ED - Edmund Burke ED - Jose A. Lozano ED - Jim Smith ED - Juan J. Merelo-Guerv\'os ED - John A. Bullinaria ED - Jonathan Rowe ED - Peter Ti\v{n}o Ata Kab\'an ED - Hans-Paul Schwefel KW - evolutionary computation KW - problem evolving KW - travelling salesman AB - This paper introduces a generator that creates problem instances for the Euclidean symmetric travelling salesman problem. To fit real world problems, we look at maps consisting of clustered nodes. Uniform random sampling methods do not result in maps where the nodes are spread out to form identifiable clusters. To improve upon this, we propose an evolutionary algorithm that uses the layout of nodes on a map as its genotype. By optimising the spread until a set of constraints is satisfied, we are able to produce better clustered maps, in a more robust way. When varying the number of clusters in these maps and, when solving the Euclidean symmetric travelling salesman person using Chained Lin-Kernighan, we observe a phase transition in the form of an easy-hard-easy pattern. JF - LNCS PB - Springer-Verlag CY - Birmingham, UK VL - 3242 SN - 3-540-23092-0 UR - http://www.vanhemert.co.uk/files/clustered-phase-transition-tsp.tar.gz ER - TY - JOUR T1 - The Research of Relationship between Self-similar of TCP and Network Performance JF - Journal on communications Y1 - 2004 A1 - yan Liu A1 - Liangxiu Han VL - 25 IS - 4 ER - TY - JOUR T1 - Robust parameter settings for variation operators by measuring the resampling ratio: A study on binary constraint satisfaction problems JF - Journal of Heuristics Y1 - 2004 A1 - van Hemert, J. I. A1 - Bäck, T. KW - constraint satisfaction KW - evolutionary computation KW - resampling ratio AB - In this article, we try to provide insight into the consequence of mutation and crossover rates when solving binary constraint satisfaction problems. This insight is based on a measurement of the space searched by an evolutionary algorithm. From data empirically acquired we describe the relation between the success ratio and the searched space. This is achieved using the resampling ratio, which is a measure for the amount of points revisited by a search algorithm. This relation is based on combinations of parameter settings for the variation operators. We then show that the resampling ratio is useful for identifying the quality of parameter settings, and provide a range that corresponds to robust parameter settings. VL - 10 ER - TY - RPRT T1 - SPLAT: (Suffix-tree Powered Local Alignment Tool): A Full-Sensitivity Protein Database Search Program that Accelerates the Smith-Waterman Algorithm using a Generalised Suffix Tree Index. Y1 - 2004 A1 - Harding, N. J. A1 - Atkinson, M. P. JF - Department of Computer Science (DCS Tech Report TR-2003-141) PB - University of Glasgow ER - TY - CONF T1 - A Study into Ant Colony Optimization, Evolutionary Computation and Constraint Programming on Binary Constraint Satisfaction Problems T2 - Springer Lecture Notes on Computer Science Y1 - 2004 A1 - van Hemert, J. I. A1 - Solnon, C. ED - J. Gottlieb ED - G. Raidl KW - ant colony optimisation KW - constraint programming KW - constraint satisfaction KW - evolutionary computation AB - We compare two heuristic approaches, evolutionary computation and ant colony optimisation, and a complete tree-search approach, constraint programming, for solving binary constraint satisfaction problems. We experimentally show that, if evolutionary computation is far from being able to compete with the two other approaches, ant colony optimisation nearly always succeeds in finding a solution, so that it can actually compete with constraint programming. The resampling ratio is used to provide insight into heuristic algorithms performances. Regarding efficiency, we show that if constraint programming is the fastest when instances have a low number of variables, ant colony optimisation becomes faster when increasing the number of variables. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin SN - 3-540-21367-8 ER - TY - RPRT T1 - Web Service Grids: An Evolutionary Approach Y1 - 2004 A1 - Malcolm Atkinson A1 - Roure, David De A1 - Alistair Dunlop A1 - Fox, Geoffrey A1 - Henderson, Peter A1 - Tony Hey A1 - Norman Paton A1 - Newhouse, Steven A1 - Parastatidis, Savas A1 - Anne Trefethen A1 - Watson, Paul A1 - Webber, Jim AB - The UK e-Science Programme is a £250M, 5 year initiative which has funded over 100 projects. These application-led projects are under-pinned by an emerging set of core middleware services that allow the coordinated, collaborative use of distributed resources. This set of middleware services runs on top of the research network and beneath the applications we call the ‘Grid’. Grid middleware is currently in transition from pre-Web Service versions to a new version based on Web Services. Unfortunately, only a very basic set of Web Services embodied in the Web Services Interoperability proposal, WS-I, are agreed by most IT companies. IBM and others have submitted proposals for Web Services for Grids - the Web Services ResourceFramework and Web Services Notification specifications - to the OASIS organisation for standardisation. This process could take up to 12 months from March 2004 and the specifications are subject to debate and potentially significant changes. Since several significant UK e-Science projects come to an end before the end of this process, the UK therefore needs to develop a strategy that will protect the UK’s investment in Grid middleware by informing the Open Middleware Infrastructure Institute’s (OMII) roadmap and UK middleware repository in Southampton. This paper sets out an evolutionary roadmap that will allow us to capture generic middleware components from projects in a form that will facilitate migration or interoperability with the emerging Grid Web Services standards and with on-going OGSA developments. In this paper we therefore define a set of Web Services specifications - that we call ‘WS-I+’ to reflect the fact that this is a larger set than currently accepted by WS-I – that we believe will enable us to achieve the twin goals of capturing these components and facilitating migration to future standards. We believe that the extra Web Services specifications we have included in WS-I+ are both helpful in building e-Science Grids and likely to be widely accepted. JF - UK e-Science Technical Report Series ER - TY - JOUR T1 - Comparing Evolutionary Algorithms on Binary Constraint Satisfaction Problems JF - IEEE Transactions on Evolutionary Computation Y1 - 2003 A1 - Craenen, B. G. W. A1 - Eiben, A. E. A1 - van Hemert, J. I. KW - constraint satisfaction AB - Constraint handling is not straightforward in evolutionary algorithms (EA) since the usual search operators, mutation and recombination, are `blind' to constraints. Nevertheless, the issue is highly relevant, for many challenging problems involve constraints. Over the last decade numerous EAs for solving constraint satisfaction problems (CSP) have been introduced and studied on various problems. The diversity of approaches and the variety of problems used to study the resulting algorithms prevents a fair and accurate comparison of these algorithms. This paper aligns related work by presenting a concise overview and an extensive performance comparison of all these EAs on a systematically generated test suite of random binary CSPs. The random problem instance generator is based on a theoretical model that fixes deficiencies of models and respective generators that have been formerly used in the Evolutionary Computing (EC) field. VL - 7 UR - http://ieeexplore.ieee.org/xpl/abs_free.jsp?isNumber=27734&prod=JNL&arnumber=1237162&arSt=+424&ared=+444&arAuthor=+Craenen%2C+B.G.W.%3B++Eiben%2C+A.E.%3B++van+Hemert%2C+J.I.&arNumber=1237162&a_id0=1237161&a_id1=1237162&a_id2=1237163&a_id3=1237164&a_id4=12 ER - TY - CONF T1 - Dependable Grid Services T2 - UK e-Science All Hands Meeting 2003, 2-4th September, Nottingham, UK Y1 - 2003 A1 - Stuart Anderson A1 - Yin Chen A1 - Glen Dobson A1 - Stephen Hall A1 - Conrad Hughes A1 - Yong Li A1 - Sheng Qu A1 - Ed Smith A1 - Ian Sommerville A1 - Ma Tiejun ED - Proceedings of UK e-Science All Hands Meeting 2003 AB - The provision of dependable computer systems by deploying diverse, redundant components in order to mask or provide recovery from component failures has mostly been restricted to systems with very high criticality. In this paper we present an architecture and prototype implementation of an approach to providing such redundancy at low cost in service-based infrastructures. In particular we consider services that are supplied by composing a number of component services and consider how service discovery, automatic monitoring and failure detection have the potential to create composed services that are more dependable than might be possible using a straightforward approach. The work is still in its early stages and so far no evaluation of the approach has been carried out. JF - UK e-Science All Hands Meeting 2003, 2-4th September, Nottingham, UK CY - Nottingham, UK ER - TY - CONF T1 - The Design and Implementation of Grid Database Services in OGSA-DAI T2 - All Hands Meeting 2003 Y1 - 2003 A1 - Ali Anjomshoaa A1 - Antonioletti, Mario A1 - Malcolm Atkinson A1 - Rob Baxter A1 - Borley, Andrew A1 - Hong, Neil P. Chue A1 - Collins, Brian A1 - Hardman, Neil A1 - George Hicken A1 - Ally Hume A1 - Knox, Alan A1 - Mike Jackson A1 - Krause, Amrey A1 - Laws, Simon A1 - Magowan, James A1 - Charaka Palansuriya A1 - Paton, Norman W. AB - This paper presents a high-level overview of the design and implementation of the core components of the OGSA-DAI project. It describes the design decisions made, the project’s interaction with the Data Access and Integration Working Group of the Global Grid Forum and provides an overview of implementation characteristics. Further details of the implementation are provided in the extensive documentation available from the project web site. JF - All Hands Meeting 2003 CY - Nottingham, UK ER - TY - JOUR T1 - The DWMM network traffic model JF - Journal of Communication Y1 - 2003 A1 - Cong Suo A1 - Liangxiu Han VL - 24 IS - 5 ER - TY - CONF T1 - Evolving binary constraint satisfaction problem instances that are difficult to solve T2 - Proceedings of the IEEE 2003 Congress on Evolutionary Computation Y1 - 2003 A1 - van Hemert, J. I. KW - constraint satisfaction KW - problem evolving AB - We present a study on the difficulty of solving binary constraint satisfaction problems where an evolutionary algorithm is used to explore the space of problem instances. By directly altering the structure of problem instances and by evaluating the effort it takes to solve them using a complete algorithm we show that the evolutionary algorithm is able to detect problem instances that are harder to solve than those produced with conventional methods. Results from the search of the evolutionary algorithm confirm conjectures about where the most difficult to solve problem instances can be found with respect to the tightness. JF - Proceedings of the IEEE 2003 Congress on Evolutionary Computation PB - IEEE Press SN - 0-7803-7804-0 ER - TY - CONF T1 - Experiences of Designing and Implementing Grid Database Services in the OGSA-DAI project T2 - Global Grid Forum Workshop on Designing and Building Grid Services/GGF9 Y1 - 2003 A1 - Antonioletti, Mario A1 - Neil Chue Hong A1 - Ally Hume A1 - Mike Jackson A1 - Krause, Amy A1 - Jeremy Nowell A1 - Charaka Palansuriya A1 - Tom Sugden A1 - Martin Westhead AB - This paper describes the experiences of the OGSA-DAI team in designing and building a database access layer using the OGSI and the emerging DAIS GGF recommendations. This middleware is designed for enabling other UK e-Science projects that require database access and providing the basic primitives for higher-level services such as Distributed Query Processing. OGSA-DAI also intends to produce one of the required reference implementations of the DAIS specification once this becomes a proposed recommendation and, until then, scope out their ideas, provide feedback as well as directly contributing to the GGF working group. This paper enumerates the issues that have arisen in tracking the DAIS and OGSI specifications whilst developing a software distribution using the Grid services model; trying to serve the needs of the various target communities; and using the Globus Toolkit OGSI core distribution. The OGSA-DAI software distribution and more details are available from the project web site at http://www.ogsadai.org.uk/. JF - Global Grid Forum Workshop on Designing and Building Grid Services/GGF9 CY - Chicago, USA ER - TY - CONF T1 - A new permutation model for solving the graph k-coloring problem T2 - Kalmàr Workshop on Logic and Computer Science Y1 - 2003 A1 - Juhos, I. A1 - Tóth, A. A1 - Tezuka, M. A1 - Tann, P. A1 - van Hemert, J. I. KW - constraint satisfaction KW - graph colouring AB - This paper describes a novel representation and ordering model, that is aided by an evolutionary algorithm, is used in solving the graph k-coloring. A comparison is made between the new representation and an improved version of the traditional graph coloring technique DSATUR on an extensive list of graph k-coloring problem instances with different properties. The results show that our model outperforms the improved DSATUR on most of the problem instances. JF - Kalmàr Workshop on Logic and Computer Science ER - TY - CHAP T1 - Rationale for Choosing the Open Grid Services Architecture T2 - Grid Computing: Making the Global Infrastructure a Reality Y1 - 2003 A1 - Atkinson, M. ED - F. Berman ED - G. Fox ED - T. Hey JF - Grid Computing: Making the Global Infrastructure a Reality PB - John Wiley & Sons, Ltd CY - Chichester, UK SN - 9780470853191 ER - TY - JOUR T1 - Application of the methodology combined formal method with Object-Oriented technology in E-commerce JF - Journal of Computer Engineering Y1 - 2002 A1 - Liangxiu Han VL - 29 IS - z1 ER - TY - CONF T1 - Comparing Classical Methods for Solving Binary Constraint Satisfaction Problems with State of the Art Evolutionary Computation T2 - Springer Lecture Notes on Computer Science Y1 - 2002 A1 - van Hemert, J. I. ED - S. Cagnoni ED - J. Gottlieb ED - E. Hart ED - M. Middendorf ED - G. Raidl KW - constraint satisfaction AB - Constraint Satisfaction Problems form a class of problems that are generally computationally difficult and have been addressed with many complete and heuristic algorithms. We present two complete algorithms, as well as two evolutionary algorithms, and compare them on randomly generated instances of binary constraint satisfaction prob-lems. We find that the evolutionary algorithms are less effective than the classical techniques. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin ER - TY - JOUR T1 - Database indexing for large DNA and protein sequence collections JF - VLDB J. Y1 - 2002 A1 - Hunt, Ela A1 - Atkinson, Malcolm P. A1 - Irving, Robert W. VL - 11 ER - TY - CONF T1 - Measuring the Searched Space to Guide Efficiency: The Principle and Evidence on Constraint Satisfaction T2 - Springer Lecture Notes on Computer Science Y1 - 2002 A1 - van Hemert, J. I. A1 - Bäck, T. ED - J. J. Merelo ED - A. Panagiotis ED - H.-G. Beyer ED - Jos{\'e}-Luis Fern{\'a}ndez-Villaca{\~n}as ED - Hans-Paul Schwefel KW - constraint satisfaction KW - resampling ratio AB - In this paper we present a new tool to measure the efficiency of evolutionary algorithms by storing the whole searched space of a run, a process whereby we gain insight into the number of distinct points in the state space an algorithm has visited as opposed to the number of function evaluations done within the run. This investigation demonstrates a certain inefficiency of the classical mutation operator with mutation-rate 1/l, where l is the dimension of the state space. Furthermore we present a model for predicting this inefficiency and verify it empirically using the new tool on binary constraint satisfaction problems. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin SN - 3-540-44139-5 ER - TY - JOUR T1 - A network traffic model based on the cascade process JF - Journal of Mini-Micro Computer System Y1 - 2002 A1 - Liangxiu Han A1 - yan Liu A1 - Zhiwei Cen VL - 23 IS - 12 ER - TY - JOUR T1 - A new multifractal network traffic model JF - Journal of Chaos, solitons & fractals Y1 - 2002 A1 - Liangxiu Han A1 - Zhiwei Ceng A1 - Chuanshan Gao PB - Elsevier Science VL - 13 IS - 7 ER - TY - CONF T1 - Use of Evolutionary Algorithms for Telescope Scheduling T2 - Integrated Modeling of Telescopes Y1 - 2002 A1 - Grim, R. A1 - Jansen, M. L. M. A1 - Baan, A. A1 - van Hemert, J. I. A1 - de Wolf, H. ED - Torben Anderson KW - constraint satisfaction KW - scheduling AB - LOFAR, a new radio telescope, will be designed to observe with up to 8 independent beams, thus allowing several simultaneous observations. Scheduling of multiple observations parallel in time, each having their own constraints, requires a more intelligent and flexible scheduling function then operated before. In support of the LOFAR radio telescope project, and in co-operation with Leiden University, Fokker Space has started a study to investigate the suitability of the use of evolutionary algorithms applied to complex scheduling problems. After a positive familiarisation phase, we now examine the potential use of evolutionary algorithms via a demonstration project. Results of the familiarisation phase, and the first results of the demonstration project are presented in this paper. JF - Integrated Modeling of Telescopes PB - The International Society for Optical Engineering ({SPIE}) VL - 4757 ER - TY - CONF T1 - Adaptive Genetic Programming Applied to New and Existing Simple Regression Problems T2 - Springer Lecture Notes on Computer Science Y1 - 2001 A1 - Eggermont, J. A1 - van Hemert, J. I. ED - J. Miller ED - Tomassini, M. ED - P. L. Lanzi ED - C. Ryan ED - A. G. B. Tettamanzi ED - W. B. Langdon KW - data mining AB - In this paper we continue our study on adaptive genetic pro-gramming. We use Stepwise Adaptation of Weights to boost performance of a genetic programming algorithm on simple symbolic regression problems. We measure the performance of a standard GP and two variants of SAW extensions on two different symbolic regression prob-lems from literature. Also, we propose a model for randomly generating polynomials which we then use to further test all three GP variants. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin SN - 9-783540-418993 ER - TY - JOUR T1 - The characterizing network traffic based on the wavelet technique JF - Journal of Mini-Micro Computer System Y1 - 2001 A1 - Liangxiu Han A1 - Cong Suo VL - 22 IS - 9 ER - TY - CONF T1 - A Database Index to Large Biological Sequences T2 - VLDB Y1 - 2001 A1 - Hunt, Ela A1 - Atkinson, Malcolm P. A1 - Irving, Robert W. JF - VLDB ER - TY - CONF T1 - An Engineering Approach to Evolutionary Art T2 - Proceedings of the Genetic and Evolutionary Computation Conference (GECCO-2001) Y1 - 2001 A1 - van Hemert, J. I. A1 - Jansen, M. L. M. ED - Lee Spector ED - Erik D. Goodman ED - Annie Wu ED - W. B. Langdon ED - Hans-Michael Voigt ED - Mitsuo Gen ED - Sandip Sen ED - Marco Dorigo ED - Shahram Pezeshk ED - Max H. Garzon ED - Edmund Burke KW - evolutionary art AB - We present a general system that evolves art on the Internet. The system runs on a server which enables it to collect information about its usage world wide; its core uses operators and representations from genetic program-ming. We show two types of art that can be evolved using this general system. JF - Proceedings of the Genetic and Evolutionary Computation Conference (GECCO-2001) PB - Morgan Kaufmann Publishers, San Francisco ER - TY - CONF T1 - Evolutionary Computation in Constraint Satisfaction and Machine Learning --- An abstract of my PhD. T2 - Proceedings of the Brussels Evolutionary Algorithms Day (BEAD-2001) Y1 - 2001 A1 - van Hemert, J. I. ED - Anne Defaweux ED - Bernard Manderick ED - Tom Lenearts ED - Johan Parent ED - Piet van Remortel KW - constraint satisfaction KW - data mining JF - Proceedings of the Brussels Evolutionary Algorithms Day (BEAD-2001) PB - Vrije Universiteit Brussel (VUB) ER - TY - CONF T1 - A ``Futurist'' approach to dynamic environments T2 - Proceedings of the Workshops at the Genetic and Evolutionary Computation Conference, Dynamic Optimization Problems Y1 - 2001 A1 - van Hemert, J. I. A1 - Van Hoyweghen, C. A1 - Lukschandl, E. A1 - Verbeeck, K. ED - J. Branke ED - Th. B{\"a}ck KW - dynamic problems AB - The optimization of dynamic environments has proved to be a difficult area for Evolutionary Algorithms. As standard haploid populations find it difficult to track a moving target, diffKerent schemes have been suggested to improve the situation. We study a novel approach by making use of a meta learner which tries to predict the next state of the environment, i.e. the next value of the goal the individuals have to achieve, by making use of the accumulated knowledge from past performance. JF - Proceedings of the Workshops at the Genetic and Evolutionary Computation Conference, Dynamic Optimization Problems PB - Morgan Kaufmann Publishers, San Francisco ER - TY - CONF T1 - A new multifractal traffic model based on the wavelet transform T2 - ISCA 14th International Conference on Parallel and Distributed Computing systems Y1 - 2001 A1 - Chuanshan Gao A1 - Liangxiu Han JF - ISCA 14th International Conference on Parallel and Distributed Computing systems CY - Texas, USA ER - TY - CHAP T1 - Scalable and Recoverable Implementation of Object Evolution for the PJama1 Platform T2 - Persistent Object Systems: Design, Implementation, and Use 9th International Workshop, POS-9 Lillehammer, Norway, September 6–8, 2000 Revised Papers Y1 - 2001 A1 - Atkinson, M. P. A1 - Dmitriev, M. A. A1 - Hamilton, C. A1 - Printezis, T. ED - Graham N. C. ED - Kirby, Alan Dearle ED - Dag I. K. Sjøberg AB - PJama1 is the latest version of an orthogonally persistent platform for Java. It depends on a new persistent object store, Sphere, and provides facilities for class evolution. This evolution technology supports an arbitrary set of changes to the classes, which may have arbitrarily large populations of persistent objects. We verify that the changes are safe. When there are format changes, we also convert all of the instances, while leaving their identities unchanged. We aspire to both very large persistent object stores and freedom for developers to specify arbitrary conversion methods in Java to convey information from old to new formats. Evolution operations must be safe and the evolution cost should be approximately linear in the number of objects that must be reformatted. In order that these conversion methods can be written easily, we continue to present the pre-evolution state consistently to Java executions throughout an evolution. At the completion of applying all of these transformations, we must switch the store state to present only the post-evolution state, with object identity preserved. We present an algorithm that meets these requirements for eager, total conversion. This paper focuses on the mechanisms built into Sphere to support safe, atomic and scalable evolution. We report our experiences in using this technology and include a preliminary set of performance measurements. JF - Persistent Object Systems: Design, Implementation, and Use 9th International Workshop, POS-9 Lillehammer, Norway, September 6–8, 2000 Revised Papers T3 - Lecture Notes in Computer Science PB - Springer VL - 2135 UR - http://www.springerlink.com/content/09hx07h9lw0p1h82/?p=2bc20319905146bab8ba93b2fcc8cc01&pi=23 ER - TY - CONF T1 - Constraint Satisfaction Problems and Evolutionary Algorithms: A Reality Check T2 - Proceedings of the Twelfth Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'00) Y1 - 2000 A1 - van Hemert, J. I. ED - van den Bosch, A. ED - H. Weigand KW - constraint satisfaction AB - Constraint satisfaction has been the subject of many studies. Different areas of research have tried to solve all kind of constraint problems. Here we will look at a general model for constraint satisfaction problems in the form of binary constraint satisfaction. The problems generated from this model are studied in the research area of constraint programming and in the research area of evolutionary computation. This paper provides an empirical comparison of two techniques from each area. Basically, this is a check on how well both areas are doing. It turns out that, although evolutionary algorithms are doing well, classic approaches are still more successful. JF - Proceedings of the Twelfth Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'00) PB - BNVKI, Dutch and the Belgian AI Association ER - TY - JOUR T1 - De Creatieve Computer JF - AIgg Kennisgeving Y1 - 2000 A1 - van Hemert, J. I. KW - evolutionary art AB - Here we show an application that generates images resembling art as it was produced by Mondriaan, a Dutch artist, well known for his minimalistic and pure abstract pieces of art. The current version generates images using a linear chromosome and a recursive function as a decoder. PB - Artifici{\"e}le Intelligentie gebruikers groep VL - 13 N1 - invited article (in Dutch) ER - TY - CONF T1 - Measurement and analysis of IP network traffic T2 - In Proceedings of the 3th International Asia-Pacific Web Conference Y1 - 2000 A1 - cen, Z A1 - Gao, C A1 - Cong S A1 - Han, L JF - In Proceedings of the 3th International Asia-Pacific Web Conference CY - xi'an China ER - TY - CONF T1 - Scalable and Recoverable Implementation of Object Evolution for the PJama1 Platform T2 - POS Y1 - 2000 A1 - Atkinson, Malcolm P. A1 - Dmitriev, Misha A1 - Hamilton, Craig A1 - Printezis, Tony JF - POS ER - TY - CONF T1 - Stepwise Adaptation of Weights for Symbolic Regression with Genetic Programming T2 - Proceedings of the Twelfth Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'00) Y1 - 2000 A1 - Eggermont, J. A1 - van Hemert, J. I. ED - van den Bosch, A. ED - H. Weigand KW - data mining KW - genetic programming AB - In this paper we continue study on the Stepwise Adaptation of Weights (SAW) technique. Previous studies on constraint satisfaction and data clas-sification have indicated that SAW is a promising technique to boost the performance of evolutionary algorithms. Here we use SAW to boost per-formance of a genetic programming algorithm on simple symbolic regression problems. We measure the performance of a standard GP and two variants of SAW extensions on two different symbolic regression problems. JF - Proceedings of the Twelfth Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'00) PB - BNVKI, Dutch and the Belgian AI Association ER - TY - CONF T1 - Adapting the Fitness Function in GP for Data Mining T2 - Springer Lecture Notes on Computer Science Y1 - 1999 A1 - Eggermont, J. A1 - Eiben, A. E. A1 - van Hemert, J. I. ED - R. Poli ED - P. Nordin ED - W. B. Langdon ED - T. C. Fogarty KW - data mining KW - genetic programming AB - In this paper we describe how the Stepwise Adaptation of Weights (SAW) technique can be applied in genetic programming. The SAW-ing mechanism has been originally developed for and successfully used in EAs for constraint satisfaction problems. Here we identify the very basic underlying ideas behind SAW-ing and point out how it can be used for different types of problems. In particular, SAW-ing is well suited for data mining tasks where the fitness of a candidate solution is composed by `local scores' on data records. We evaluate the power of the SAW-ing mechanism on a number of benchmark classification data sets. The results indicate that extending the GP with the SAW-ing feature increases its performance when different types of misclassifications are not weighted differently, but leads to worse results when they are. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin SN - 3-540-65899-8 ER - TY - CONF T1 - Comparing genetic programming variants for data classification T2 - Proceedings of the Eleventh Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'99) Y1 - 1999 A1 - Eggermont, J. A1 - Eiben, A. E. A1 - van Hemert, J. I. ED - E. Postma ED - M. Gyssens KW - classification KW - data mining KW - genetic programming AB - This article is a combined summary of two papers written by the authors. Binary data classification problems (with exactly two disjoint classes) form an important application area of machine learning techniques, in particular genetic programming (GP). In this study we compare a number of different variants of GP applied to such problems whereby we investigate the effect of two significant changes in a fixed GP setup in combination with two different evolutionary models JF - Proceedings of the Eleventh Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'99) PB - BNVKI, Dutch and the Belgian AI Association ER - TY - CONF T1 - A comparison of genetic programming variants for data classification T2 - Springer Lecture Notes on Computer Science Y1 - 1999 A1 - Eggermont, J. A1 - Eiben, A. E. A1 - van Hemert, J. I. ED - D. J. Hand ED - J. N. Kok ED - M. R. Berthold KW - classification KW - data mining KW - genetic programming AB - In this paper we report the results of a comparative study on different variations of genetic programming applied on binary data classification problems. The first genetic programming variant is weighting data records for calculating the classification error and modifying the weights during the run. Hereby the algorithm is defining its own fitness function in an on-line fashion giving higher weights to `hard' records. Another novel feature we study is the atomic representation, where `Booleanization' of data is not performed at the root, but at the leafs of the trees and only Boolean functions are used in the trees' body. As a third aspect we look at generational and steady-state models in combination of both features. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin SN - 3-540-66332-0 ER - TY - CONF T1 - Mondriaan Art by Evolution T2 - Proceedings of the Eleventh Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'99) Y1 - 1999 A1 - van Hemert, J. I. A1 - Eiben, A. E. ED - E. Postma ED - M. Gyssens KW - evolutionary art AB - Here we show an application that generates images resembling art as it was produced by Mondriaan, a Dutch artist, well known for his minimalistic and pure abstract pieces of art. The current version generates images using a linear chromosome and a recursive function as a decoder. JF - Proceedings of the Eleventh Belgium/Netherlands Conference on Artificial Intelligence (BNAIC'99) PB - BNVKI, Dutch and the Belgian AI Association ER - TY - JOUR T1 - Neural network applied to the prediction of the failure stress for pressurized cylinders containing defects JF - International Journal of Pressure Vessels and Piping Y1 - 1999 A1 - Lianghao Han A1 - Liangxiu Han A1 - zengdian Liu PB - Elsevier VL - 76 IS - 4 ER - TY - CONF T1 - Population dynamics and emerging features in AEGIS T2 - Proceedings of the Genetic and Evolutionary Computation Conference Y1 - 1999 A1 - Eiben, A. E. A1 - Elia, D. A1 - van Hemert, J. I. ED - W. Banzhaf ED - J. Daida ED - Eiben, A. E. ED - M. H. Garzon ED - V. Honavar ED - M. Jakiela ED - R. E. Smith KW - dynamic problems AB - We describe an empirical investigation within an artificial world, aegis, where a population of animals and plants is evolving. We compare different system setups in search of an `ideal' world that allows a constantly high number of inhabitants for a long period of time. We observe that high responsiveness at individual level (speed of movement) or population level (high fertility) are `ideal'. Furthermore, we investigate the emergence of the so-called mental features of animals determining their social, consumptional and aggressive behaviour. The tests show that being socially oriented is generally advantageous, while agressive behaviour only emerges under specific circumstances. JF - Proceedings of the Genetic and Evolutionary Computation Conference PB - Morgan Kaufmann Publishers, San Francisco ER - TY - JOUR T1 - Questions considered in object-oriented software quality metrics based on Java environment JF - Journal of East China University of Science and Technology Y1 - 1999 A1 - Liangxiu Han PB - East China University of Science and Technology ER - TY - CHAP T1 - SAW-ing EAs: adapting the fitness function for solving constrained problems T2 - New ideas in optimization Y1 - 1999 A1 - Eiben, A. E. A1 - van Hemert, J. I. ED - D. Corne ED - M. Dorigo ED - F. Glover KW - constraint satisfaction AB - In this chapter we describe a problem independent method for treating constrain ts in an evolutionary algorithm. Technically, this method amounts to changing the defini tion of the fitness function during a run of an EA, based on feedback from the search pr ocess. Obviously, redefining the fitness function means redefining the problem to be sol ved. On the short term this deceives the algorithm making the fitness values deteriorate , but as experiments clearly indicate, on the long run it is beneficial. We illustrate t he power of the method on different constraint satisfaction problems and point out other application areas of this technique. JF - New ideas in optimization PB - McGraw-Hill, London ER - TY - CONF T1 - Extended abstract: Solving Binary Constraint Satisfaction Problems using Evolutionary Algorithms with an Adaptive Fitness Function T2 - Proceedings of the Xth Netherlands/Belgium Conference on Artificial Intelligence (NAIC'98) Y1 - 1998 A1 - Eiben, A. E. A1 - van Hemert, J. I. A1 - Marchiori, E. A1 - Steenbeek, A. G. ED - la Poutré, J. A. ED - van den Herik, J. KW - constraint satisfaction JF - Proceedings of the Xth Netherlands/Belgium Conference on Artificial Intelligence (NAIC'98) PB - BNVKI, Dutch and the Belgian AI Association N1 - Abstract of \cite{EHMS98} ER - TY - JOUR T1 - Graph Coloring with Adaptive Evolutionary Algorithms JF - Journal of Heuristics Y1 - 1998 A1 - Eiben, A. E. A1 - van der Hauw, J. K. A1 - van Hemert, J. I. KW - constraint satisfaction KW - graph colouring AB - This paper presents the results of an experimental investigation on solving graph coloring problems with Evolutionary Algorithms (EA). After testing different algorithm variants we conclude that the best option is an asexual EA using order-based representation and an adaptation mechanism that periodically changes the fitness function during the evolution. This adaptive EA is general, using no domain specific knowledge, except, of course, from the decoder (fitness function). We compare this adaptive EA to a powerful traditional graph coloring technique DSatur and the Grouping GA on a wide range of problem instances with different size, topology and edge density. The results show that the adaptive EA is superior to the Grouping GA and outperforms DSatur on the hardest problem instances. Furthermore, it scales up better with the problem size than the other two algorithms and indicates a linear computational complexity. PB - Kluwer Academic Publishers VL - 4 ER - TY - CONF T1 - Solving Binary Constraint Satisfaction Problems using Evolutionary Algorithms with an Adaptive Fitness Function T2 - Springer Lecture Notes on Computer Science Y1 - 1998 A1 - Eiben, A. E. A1 - van Hemert, J. I. A1 - Marchiori, E. A1 - Steenbeek, A. G. ED - Eiben, A. E. ED - Th. B{\"a}ck ED - M. Schoenauer ED - H.-P. Schwefel KW - constraint satisfaction AB - This paper presents a comparative study of Evolutionary Algorithms (EAs) for Constraint Satisfaction Problems (CSPs). We focus on EAs where fitness is based on penalization of constraint violations and the penalties are adapted during the execution. Three different EAs based on this approach are implemented. For highly connected constraint networks, the results provide further empirical support to the theoretical prediction of the phase transition in binary CSPs. JF - Springer Lecture Notes on Computer Science PB - Springer-Verlag, Berlin ER - TY - JOUR T1 - On Zero-symmetric BZ-algebras JF - Journal of East China University of Science and Technology Y1 - 1997 A1 - Wang, Y. A1 - Liangxiu Han PB - East China University of Science and Technology VL - 23 IS - 6 ER -