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Developing an Ontology for Psychosis. NeuroPsyGrid is a collaborative project which aims to address key issues in data interoperability in mental health sciences by developing a shared domain ontology.
The aims of the Collaboration are:
to harmonise and accelerate the work of PsyGrid and NeuroGrid towards a common database, a shared metadata model and an ontology of terms for psychosis relevant clinical and biological data, with a particular focus on changes around the time of onset.
to assess the viability and usefulness of this system by combining existing first episode psychosis (FEP) data from the Edinburgh High Risk Study (EHRS) and other FEP data sets;
to extend the PsyGrid structural magnetic resonance imaging (sMRI) 3-site reliability study to include two centres from NeuroGrid, to repeat the scans one year later and include a functional MRI (fMRI) reliability study, to inform future multi-centre imaging studies; and
to ensure that these data acquisition, storage and access arrangements are compatible with other major national developments such as the Mental Health Research Network (MHRN) and the Mental Health Minimum Data-set in the UK, and international initiatives such as the Brain Informatics Research Network (BIRN) in the USA; and thus
to put UK clinical neuroscience researchers in a better position to mount multi-centre clinical studies and trials with neuro-imaging biomarkers with this informatics platform.