Positions Vacant
Science Literature Curators
- 2 Part-Time posts

 

Post Reference Number: 841

Location: Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK

Salary: Dependent upon experience

General Information:

The Genes to Cognition Programme (G2C) is a joint scientific research programme at the University of Edinburgh and the Wellcome Trust Sanger Institute, Cambridge, which is funded by The Wellcome Trust for 5 years.

G2C aims to establish a framework for studying genes, brain and behaviour in order to link basic molecular research from genomes and experimental genetic organisms with human clinical studies of cognition. We will collect and integrate data in the areas of psychiatry, human and mouse psychology, cellular neurophysiology, cell biology, proteomics, biochemistry, molecular biology, human and mouse genetics and genomics. Bioinformatics will be used to create new tools for presenting this diverse data in novel relationships that will facilitate mining of information across existing boundaries in neuroscience. We will conduct a systematic study of mutations and polymorphisms in mouse and human genes, and explore how these genes influence a broad range of phenotypes including: gene expression, protein function, physiology and behaviour, especially cognition.

Applications are invited to join a team of scientists studying the molecular basis of cognitive function and behaviour. The research programme will focus on molecules expressed at the synapse of nerve cells in the mammalian nervous system. The programme is broadly interactive, studying genes, proteins, neurons, electrophysiology and behaviour utilising the mouse system. The programme is linked to a human genetics programme.

Post Information:

2 Part-time positions are available for Scientific Literature Curators. The applicants will be constructing databases containing information on synaptic plasticity and its molecular basis, and information on behaviours. This information will be mined from the published literature using available search engines and specific tools created by programmers within the G2C consortium.

This is a team role and applicants will be expected to integrate with other team members and disciplines so the ideal candidate should possess excellent organisational and communication skills.

 

Key Activities:

1. Identification of relevant scientific papers for inclusion in a database of synaptic plasticity (LTP / LTD), animal behaviour and other areas of neuroscience.
2. Collection of information on the performance of mutant mice in behavioural assays.
3. Assist in creation of a web-based system for the analysis and use of the database.
4. Assist with the analysis of the database and linking to other available databases, such as the Protein-Protein Interaction Database (PPID)
5. Assist with the creation of a partially automatic text-mining project aimed at retrieving data from scientific papers in bulk for future compilation into a larger, more complete database.

Qualifications:

Honours degree in Neuroscience (or similar knowledge of neuroscience) is essential.

 

Essential:

Computer literacy is essential, along with a good understanding of Microsoft Excel.

Good communication skills.

Good attention to detail.

Ability to work without extensive supervision.

Ability to integrate and coordinate with other lab members, teams and disciplines.

 

Desirable:

Knowledge of database design and construction is preferred.

 


More Information:

For more information on this position please contact G2C Admin.

Closing Date: Friday 5 November 2004

To Apply:

To apply for this position please send:

  • a full CV
  • the contact details (including email addresses) of at least two referees
a covering letter quoting the Post Reference Number above. Please state clearly which position you wish to be considered for.

Applications should be sent to:
Human Resources
Wellcome Trust Sanger Institute
Hinxton
Cambridge CB10 1SA

United Kingdom

humanresources@sanger.ac.uk
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