Positions
Vacant
Science Literature Curators
- 2 Part-Time posts
Post
Reference Number: 841
Location:
Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK
Salary:
Dependent upon experience
General
Information:
The
Genes to Cognition Programme (G2C) is a joint scientific research programme
at the University of Edinburgh and the Wellcome Trust Sanger Institute,
Cambridge, which is funded by The Wellcome Trust for 5 years.
G2C
aims to establish a framework for studying genes, brain and behaviour
in order to link basic molecular research from genomes and experimental
genetic organisms with human clinical studies of cognition. We will
collect and integrate data in the areas of psychiatry, human and
mouse
psychology, cellular neurophysiology, cell biology, proteomics, biochemistry,
molecular biology, human and mouse genetics and genomics. Bioinformatics
will be used to create new tools for presenting this diverse data
in
novel relationships that will facilitate mining of information across
existing boundaries in neuroscience. We will conduct a systematic
study
of mutations and polymorphisms in mouse and human genes, and explore
how these genes influence a broad range of phenotypes including:
gene
expression, protein function, physiology and behaviour, especially
cognition.
Applications
are invited to join a team of scientists studying the molecular basis
of cognitive function and behaviour. The research programme will focus
on molecules expressed at the synapse of nerve cells in the mammalian
nervous system. The programme is broadly interactive, studying genes,
proteins, neurons, electrophysiology and behaviour utilising the mouse
system. The programme is linked to a human genetics programme.
Post
Information:
2 Part-time
positions are available for Scientific Literature Curators. The
applicants will be constructing databases containing information
on synaptic plasticity and its molecular basis, and information
on behaviours.
This information will be mined from the published literature using
available search engines and specific tools created by programmers
within the G2C consortium.
This is a team role and applicants will be expected to integrate with
other team members and disciplines so the ideal candidate should possess
excellent organisational and communication skills.
Key
Activities:
1. Identification
of relevant scientific papers for inclusion in a database of synaptic
plasticity (LTP / LTD), animal
behaviour and other areas of neuroscience.
2. Collection
of information on the performance of mutant mice in behavioural assays.
3. Assist
in creation of a web-based system for the analysis and use of the
database.
4. Assist
with the analysis of the database and linking to other available
databases, such as the Protein-Protein
Interaction Database (PPID)
5. Assist with the creation of a partially automatic text-mining
project aimed at retrieving data from scientific papers in bulk for
future compilation into a larger, more complete database.